Literature DB >> 7426393

The effect of acetylsalicylic acid (ASA) on the development of atherosclerotic lesions in miniature swine.

P Clopath.   

Abstract

A study was undertaken to determine the effects of acetylsalicylic acid (ASA) on the development of injury-induced atherosclerosis in swine. Treatment of mini-pigs with 30 mg/kg of ASA twice daily for 4 weeks significantly inhibited intimal thickening caused by 2 consecutive balloonings. The effect was accompanied by a 30% reduction in aortic collagen. ASA thus appears to exert a protective effect in injury-induced atherosclerosis.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7426393      PMCID： PMC2041606     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  14 in total

1.  Cultured human skin fibroblasts and arterial cells produce a labile platelet-inhibitory prostaglandin.

Authors:  N L Baenziger; M J Dillender; P W Majerus
Journal:  Biochem Biophys Res Commun       Date:  1977-09-09       Impact factor: 3.575

Review 2.  Clinical pharmacology of platelets.

Authors:  M A Packham; J F Mustard
Journal:  Blood       Date:  1977-10       Impact factor: 22.113

Review 3.  The morphogenesis and fate of potential and early atherosclerotic lesions in man.

Authors:  M D Haust
Journal:  Hum Pathol       Date:  1971-03       Impact factor: 3.466

4.  Aspirin selectively inhibits prostaglandin production in human platelets.

Authors:  J B Smith; A L Willis
Journal:  Nat New Biol       Date:  1971-06-23

5.  A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro.

Authors:  R Ross; J Glomset; B Kariya; L Harker
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

6.  Inhibition of injury induced thromboatherosclerotic lesions by anti-platelet serum in rabbits.

Authors:  S Moore; R J Friedman; D P Singal; J Gauldie; M A Blajchman; R S Roberts
Journal:  Thromb Haemost       Date:  1976-02-29       Impact factor: 5.249

7.  Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.

Authors:  R Ross; J A Glomset
Journal:  Science       Date:  1973-06-29       Impact factor: 47.728

8.  The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization.

Authors:  R J Friedman; M B Stemerman; B Wenz; S Moore; J Gauldie; M Gent; M L Tiell; H Spaet
Journal:  J Clin Invest       Date:  1977-11       Impact factor: 14.808

9.  Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation.

Authors:  S Moncada; E A Higgs; J R Vane
Journal:  Lancet       Date:  1977-01-01       Impact factor: 79.321

10.  Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Authors:  M Hamberg; J Svensson; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205
View more
  2 in total

Review 1.  Failure to Launch: Targeting Inflammation in Acute Coronary Syndromes.

Authors:  Jennifer A Rymer; L Kristin Newby
Journal:  JACC Basic Transl Sci       Date:  2017-08-28

2.  Platelet function testing in pigs using the Multiplate® Analyzer.

Authors:  Sarah Heringer; Lisa Kabelitz; Martin Kramer; Omid Nikoubashman; Marc A Brockmann; Stefanie Kirschner; Martin Wiesmann
Journal:  PLoS One       Date:  2019-08-29       Impact factor: 3.240
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.