Literature DB >> 7426302

Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.

H Pehamberger, H Ludwig, P Pötzi, W Knapp.   

Abstract

Monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) was tested in 23 patients with histologically proven Hodgkin's disease and 29 healthy normal controls. Seven patients presented with active and 16 with inactive disease. The lytic capacity of the individual monocytes was significantly (P < 0.02) higher in patients with Hodgkin's disease than in normals. However, no significant difference was found between the numbers of monocytes in both groups of individuals, as determined by non-specific esterase staining. No correlation was found between the lytic capacity of monocytes and the activity of the disease.

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Year:  1980        PMID: 7426302      PMCID: PMC2010310          DOI: 10.1038/bjc.1980.141

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  17 in total

1.  Comparison of multiple in vivo and in vitro parameters in untreated patients with Hodgkin's disease.

Authors:  D C Case; J A Hansen; E Corrales; C W Young; B Dupont; C M Pinsky; R A Good
Journal:  Cancer       Date:  1976-10       Impact factor: 6.860

2.  Rosette-forming lymphocytes in Hodgkin's disease.

Authors:  G Cohnen; W Augener; G Brittinger; S D Douglas
Journal:  N Engl J Med       Date:  1973-10-18       Impact factor: 91.245

3.  Impaired delayed-hypersensitivity responses in 154 patients with untreated Hodgkin's disease.

Authors:  J R Eltringham; H S Kaplan
Journal:  Natl Cancer Inst Monogr       Date:  1973-05

4.  Delayed hypersensitivity in Hodgkin's disease. A study of 103 untreated patients.

Authors:  R C Young; M P Corder; H A Haynes; V T DeVita
Journal:  Am J Med       Date:  1972-01       Impact factor: 4.965

5.  Monocyte-mediated antibody-dependent cellular cytotoxicity: a clinical test of monocyte function.

Authors:  D G Poplack; G D Bonnard; B J Holiman; R M Blaese
Journal:  Blood       Date:  1976-12       Impact factor: 22.113

6.  Hodgkin's disease. An immunodepleting and immunosuppressive disorder.

Authors:  J J Twomey; A H Laughter; S Farrow; C C Douglass
Journal:  J Clin Invest       Date:  1975-08       Impact factor: 14.808

7.  Monocytes and macrophages in malignant melanoma. I. Peripheral blood macrophage precursors.

Authors:  G A Currie; D W Hedley
Journal:  Br J Cancer       Date:  1977-07       Impact factor: 7.640

8.  Abnormalitieis of monocyte chemotaxis in patients with melanoma: effects of immunotherapy and tumor removal.

Authors:  R Snyderman; H F Seigler; L Meadows
Journal:  J Natl Cancer Inst       Date:  1977-01       Impact factor: 13.506

9.  Reduced monocyte phagocytosis in patients with advanced Hodgkin's disease and lymphosarcoma.

Authors:  D Urbanitz; I Fechner; R Gross
Journal:  Klin Wochenschr       Date:  1975-05-01

10.  Immunological capacity of lymphocytes from untreated patients with Hodgkin's disease evaluated in mixed lymphocyte culture.

Authors:  M Björkholm; G Holm; H Mellstedt; D Pettersson
Journal:  Clin Exp Immunol       Date:  1975-12       Impact factor: 4.330

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  4 in total

1.  Monocyte antibody-dependent cellular cytotoxicity in cancer patients.

Authors:  N J De Young; P G Gill
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

2.  Destruction of IgG anti-A sensitized erythrocytes by mononuclear leucocytes from normal and ABO haemolytic disease affected infants.

Authors:  E L Romano; M L Rossi Devivo; A Soyano; J Linares
Journal:  Clin Exp Immunol       Date:  1984-02       Impact factor: 4.330

3.  Spontaneous and antibody-dependent cellular cytotoxicity by lymphocyte subpopulations in peripheral blood and spleen from adult untreated patients with Hodgkin's disease.

Authors:  S Gupta; G Fernandes
Journal:  Clin Exp Immunol       Date:  1981-07       Impact factor: 4.330

4.  Antibody-dependent cell-mediated cytotoxicity using a murine monoclonal antibody against human colorectal cancer in cancer patients.

Authors:  K Takamuku; T Akiyoshi; H Tsuji
Journal:  Cancer Immunol Immunother       Date:  1987       Impact factor: 6.968

  4 in total

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