Literature DB >> 7426190

Prenylamine-induced ventricular tachycardia and syncope controlled by ventricular pacing.

E Grenadier, S Keidar, G Alpan, A Marmor, A Palant.   

Abstract

We describe eight patients treated for angina with prenylamine who developed life-threatening ventricular arrhythmias after QT interval prolongation. When prenylamine administration was stopped QT interval shortened to within normal values, while the ventricular arrhythmias were controlled by a temporary ventricular pacemaker and disappeared after several days. We stress the importance of surveillance of the QT interval and ventricular arrhythmias in patients receiving long-term treatment with prenylamine.

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Year:  1980        PMID： 7426190      PMCID： PMC482406          DOI： 10.1136/hrt.44.3.330

Source DB:  PubMed          Journal:  Br Heart J        ISSN： 0007-0769


  19 in total

1.  Ventricular tachycardia: a new iatrogenic possibility.

Authors:  P Fazzini; F Marchi
Journal:  Am Heart J       Date:  1975-12       Impact factor: 4.749

2.  Ventricular arrhythmias caused by prenylamine.

Authors:  R Puritz; M A Henderson; S N Baker; D A Chamberlain
Journal:  Br Med J       Date:  1977-09-03

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Authors:  T R Evans; P V Curry; D H Fitchett; D M Krikler
Journal:  J Electrocardiol       Date:  1976       Impact factor: 1.438

4.  Prenylamine in treatment of angina.

Authors:  H Tucker; P Carson; N Bass; J Massey
Journal:  Br Heart J       Date:  1974-10

5.  Lidocaine-induced heart block in patients with bundle branch block.

Authors:  P K Gupta; E Lichstein; K D Chadda
Journal:  Am J Cardiol       Date:  1974-04       Impact factor: 2.778

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Authors:  P F Fazzini; F Marchi; P Pucci
Journal:  G Ital Cardiol       Date:  1973

7.  Angina pectoris with syncope due to paroxysmal atrioventricular block: role of ischaemia. Report of two cases.

Authors:  P Chiche; R Haiat; P Steff
Journal:  Br Heart J       Date:  1974-06

8.  Effect of prenylamine in angina pectoris.

Authors:  J B Stoker
Journal:  Br J Clin Pract       Date:  1968-09

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Authors:  R Picard; P Auzepy; J P Chauvin
Journal:  Ann Cardiol Angeiol (Paris)       Date:  1971 Sep-Oct

10.  Thioridazine (mellaril)-induced ventricular tachycardia controlled with an artificial pacemaker.

Authors:  F W Schoonmaker; R T Osteen; J C Greenfield
Journal:  Ann Intern Med       Date:  1966-11       Impact factor: 25.391
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  2 in total

Review 1.  Withdrawal of prenylamine: perspectives on pharmacological, clinical and regulatory outcomes following the first QT-related casualty.

Authors:  Rashmi R Shah; Peter D Stonier
Journal:  Ther Adv Drug Saf       Date:  2018-06-18

Review 2.  Toward a broader view of mechanisms of drug cardiotoxicity.

Authors:  Polina Mamoshina; Blanca Rodriguez; Alfonso Bueno-Orovio
Journal:  Cell Rep Med       Date:  2021-03-16
  2 in total

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