Literature DB >> 7423547

Induction of zinc-thionein in rat liver and kidneys by zinc loading as studied at isometallothionein levels.

K T Suzuki, M Yamamura.   

Abstract

Zinc acetate was injected i.p. into female rats to try to clarify the detailed induction and degradation pathways of zinc-thionein (Zn-th) at isometallothionein levels in liver and kidneys. Injected zinc in serum decreased with the induction of Zn-th in the liver and kidneys, and the amounts of Zn-th in both tissues attained maxima 24 h after injection. The relative ratios of isometallothioneins changed with time in both tissues. The changes are compared with those of cadmium (Cd) loading.

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Year:  1980        PMID: 7423547     DOI: 10.1016/0378-4274(80)90103-4

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  3 in total

1.  Amino acid sequence and comparative antigenicity of chicken metallothionein.

Authors:  C C McCormick; C S Fullmer; J S Garvey
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

2.  A comparison of isometallothionein synthesis in rat liver after partial hepatectomy and parenteral zinc injection.

Authors:  K Cain; B L Griffiths
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

3.  Regulation of the isoforms of metallothionein.

Authors:  C D Klaassen; L D Lehman-McKeeman
Journal:  Biol Trace Elem Res       Date:  1989 Jul-Sep       Impact factor: 3.738

  3 in total

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