Brown amiotic fluid in congenital erythropoietic porphyria.

Brown amniotic fluid due to congenital erythropoietic porphyria has been observed at the 15th week of pregnancy in a fetus proved after abortion to have the disease. The color is produced by abnormal porphyrins resulting from a deficiency of uroporphyrin cosynthetase. The mother, a carrier of the autosomal recessive gene, has since delivered a normal infant whose amniotic fluid was unremarkable.