Literature DB >> 7420404

High incidence and heterogeneity of functional defects of the alternative pathway of complement among atopic children.

A G Siccardi, M M Marconi, F A Ferrari, A Fortunato, A Giannetti, F T Sacchi, A Beretta, A G Ugazio, S D Jayakar.   

Abstract

Two separate functional defects of the alternate pathway of complement (defective yeast opsonisation and defective rabbit erythrocyte lysis) are very frequent (of the order of 55% for the former and 35% for the latter) among atopic children and their unaffected relatives. The defects are independent of each other and of sex, age, season of sampling, type of atopic syndrome and IgE level. The alternative pathway initiation mechanism is probably involved in both defects.

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Year:  1980        PMID: 7420404

Source DB:  PubMed          Journal:  J Clin Lab Immunol        ISSN: 0141-2760


  3 in total

1.  Staphylocidal defect of polymorphonuclear leukocytes in a patient with leprechaunism.

Authors:  F Sacchi; G Maggiore; E Bianchi; G Marseglia; M Marconi; A G Ugazio; A G Siccardi
Journal:  Eur J Pediatr       Date:  1981-09       Impact factor: 3.183

2.  Serum bacterial reaction by the alternative pathway of complement: potentiation by target multiplicity and modulation by serum factors.

Authors:  A Fietta; A Fortunato; C Dos Santos; F Grassi; A G Siccardi
Journal:  Infect Immun       Date:  1981-09       Impact factor: 3.441

3.  Defective bactericidal reaction by the alternative pathway of complement in atopic patients.

Authors:  A G Siccardi; A Fortunato; M Marconi; C Dos Santos; F Grassi; F Sacchi; A Fietta
Journal:  Infect Immun       Date:  1981-09       Impact factor: 3.441

  3 in total

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