Literature DB >> 7418829

The role of hyperoxygenation in facilitating the induction of pulmonary histiocytosis by low doses of chlorphentermine.

S Kacew, R Narbaitz.   

Abstract

Hyperoxygenation modified the susceptibility of neonatal rat lung to respond to chlorphenatermine with an accumulation of hypertrophic macrophages, a morphologic change undetected when an anorectic drug was given alone. Implications of this observation for pediatrics are discussed.

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Year:  1980        PMID: 7418829     DOI: 10.1007/bf01970132

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  7 in total

1.  A comparative ultrastructural and biochemical study between the effects of chlorphentermine and phentermine on rat lung.

Authors:  S Kacew; R Narbaitz
Journal:  Exp Mol Pathol       Date:  1977-08       Impact factor: 3.362

2.  Drug-induced foam cell reactions in rats. I. Histopathologic and cytochemical observations after treatment with chlorphentermine, RMI 10.393 and Ro 4-4318.

Authors:  D Karabelnik; G Zbinden; E Baumgartner
Journal:  Toxicol Appl Pharmacol       Date:  1974-02       Impact factor: 4.219

3.  Biochemical and morphologic investigation of the influence of chlorphentermine and subsequent withdrawal on newborn rat lung.

Authors:  S Kacew; R Narbaitz; T C Dubas
Journal:  Toxicol Appl Pharmacol       Date:  1979-02       Impact factor: 4.219

4.  Oxygen toxicity in the newborn. The effect of prolonged 100 per cent O2 exposure on the lungs of newborn mice.

Authors:  D S Bonikos; K G Bensch; S K Ludwin; W H Northway
Journal:  Lab Invest       Date:  1975-05       Impact factor: 5.662

5.  Inhibition of butylated hydroxytoluene-induced mouse lung cell division by oxygen: time-effect and dose-effect relationships.

Authors:  H Witschi; M G Cöté
Journal:  Chem Biol Interact       Date:  1977-12       Impact factor: 5.192

6.  Oxygen toxicity: comparison of lung biochemical responses in neonatal and adult rats.

Authors:  J Yam; L Frank; R J Roberts
Journal:  Pediatr Res       Date:  1978-02       Impact factor: 3.756

7.  Effects of hyperbaric oxygen and glutathione on mammalian liver metabolism.

Authors:  D A Baeyens; M J Meier
Journal:  Aviat Space Environ Med       Date:  1978-08
  7 in total

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