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Literature DB >> 7418803

The effect of Apamin on nonadrenergic, noncholinergic nervous vasodilatations in the cat small intestine.

A Sjöqvist, D Delbro, M Jodal, O Lundgren.

Abstract

The intestinal vasodilation evoked by mechanical mucosal stimulation or by transmural electrical field stimulation was abolished by close i.a. injection of Apamin, a polypeptide originally isolated from bee venom. Apamin also blocked the vasodilatation induced by close i.a. infusion of vasoactive intestinal polypeptide (VIP). It is suggested that Apamin is a VIP receptor antagonist.

Entities: Gene

Mesh：

Substances：
Bee Venoms
Apamin

Year: 1980 PMID： 7418803 DOI： 10.1007/bf01976128

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

7 in total

1. Nervous release of vasoactive intestinal polypeptide in the gastrointestinal tract of cats: possible physiological implications.

Authors: J Fahrenkrug; U Haglund; M Jodal; O Lundgren; L Olbe; O B de Muckadell
Journal: J Physiol Date: 1978-11 Impact factor: 5.182

2. Studies on the intestinal vasodilatation observed after mechanical stimulation of the mucosa of the gut.

Authors: B Biber; O Lundgren; J Svanvik
Journal: Acta Physiol Scand Date: 1971-06

Review 3. Bee and wasp venoms.

Authors: E Habermann
Journal: Science Date: 1972-07-28 Impact factor: 47.728

1 in total

1. The effect of apamin on non-adrenergic, non-cholinergic vasodilator mechanisms in the intestines of the cat.

Authors: M Jodal; O Lundgren; A Sjöqvist
Journal: J Physiol Date: 1983-05 Impact factor: 5.182

1 in total

The effect of Apamin on nonadrenergic, noncholinergic nervous vasodilatations in the cat small intestine.

1. Nervous release of vasoactive intestinal polypeptide in the gastrointestinal tract of cats: possible physiological implications.

2. Studies on the intestinal vasodilatation observed after mechanical stimulation of the mucosa of the gut.

Review 3. Bee and wasp venoms.

4. Vasodilator mechanisms in the small intestine. An experimental study in the cat.

5. Intestinal vasodilatation in response to transmural electrical field stimulation.

6. The effect of apamin on the smooth muscle cells of the guinea-pig taenia coli.

7. Vasoactive intestinal polypeptide, 5-hydroxytryptamine and reflex hyperaemia in the small intestine of the cat.

1. The effect of apamin on non-adrenergic, non-cholinergic vasodilator mechanisms in the intestines of the cat.