| Literature DB >> 7416968 |
C A Kraaijeveld, H Snippe, M Harmsen, B Khader Boutahar-Trouw.
Abstract
Intracutaneous immunization of BALB/c mice with inactivated Semliki Forest virus mixed with the cationic, surface active lipid dimethyl dioctadecyl ammoniumbromide produced a strong enhancement of delayed type hypersensitivity without detectable antibodies in serum. Furthermore these mice were more protected against intraperitoneal challenge than normal immunized mice. This protection might be explained by an enhancement of cellular immunity against Semliki Forest virus. Dimethyl dioctadecyl ammoniumbromide by itself has no effect on footpad swelling, mortality and mean survival time.Entities:
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Year: 1980 PMID: 7416968 DOI: 10.1007/bf01314537
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574