Literature DB >> 7412757

Structural determinants responsible for the biological activity of (-)-emetine, (-)-cryptopleurine, and (-)-tylocrebrine: structure-activity relationship among related compounds.

R S Gupta, J J Krepinsky, L Siminovitch.   

Abstract

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Year:  1980        PMID： 7412757

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN： 0026-895X            Impact factor:   4.436


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  7 in total

1.  Molecular modeling study of tubulosine and other related ipecac alkaloids.

Authors:  M Troconis; W Ma; D E Nichols; J McLaughlin
Journal:  J Comput Aided Mol Des       Date:  1998-09       Impact factor: 3.686

2.  Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies.

Authors:  Xiaoming Yang; Qian Shi; Chin-Yu Lai; Chi-Yuan Chen; Emika Ohkoshi; Shuenn-Chen Yang; Chih-Ya Wang; Kenneth F Bastow; Tian-Shung Wu; Shiow-Lin Pan; Che-Ming Teng; Pan-Chyr Yang; Kuo-Hsiung Lee
Journal:  J Med Chem       Date:  2012-07-23       Impact factor: 7.446

3.  Antitumor agents 288: design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents.

Authors:  Xiaoming Yang; Qian Shi; Shuenn-Chen Yang; Chi-Yuan Chen; Sung-Liang Yu; Kenneth F Bastow; Susan L Morris-Natschke; Pei-Chi Wu; Chin-Yu Lai; Tian-Shung Wu; Shiow-Lin Pan; Che-Ming Teng; Jau-Chen Lin; Pan-Chyr Yang; Kuo-Hsiung Lee
Journal:  J Med Chem       Date:  2011-06-28       Impact factor: 7.446

Review 4.  Different Aspects of Emetine's Capabilities as a Highly Potent SARS-CoV-2 Inhibitor against COVID-19.

Authors:  Mehdi Valipour
Journal:  ACS Pharmacol Transl Sci       Date:  2022-05-23

5.  Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents.

Authors:  Haining Lv; Jinhong Ren; Shuanggang Ma; Song Xu; Jing Qu; Zhenjia Liu; Qing Zhou; Xiaoguang Chen; Shishan Yu
Journal:  PLoS One       Date:  2012-01-19       Impact factor: 3.240

6.  A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors.

Authors:  Peng-Xuan Ren; Wei-Juan Shang; Wan-Chao Yin; Huan Ge; Lin Wang; Xiang-Lei Zhang; Bing-Qian Li; Hong-Lin Li; Ye-Chun Xu; Eric H Xu; Hua-Liang Jiang; Li-Li Zhu; Lei-Ke Zhang; Fang Bai
Journal:  Acta Pharmacol Sin       Date:  2021-04-27       Impact factor: 7.169

Review 7.  Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies.

Authors:  Julie Dyall; Robin Gross; Jason Kindrachuk; Reed F Johnson; Gene G Olinger; Lisa E Hensley; Matthew B Frieman; Peter B Jahrling
Journal:  Drugs       Date:  2017-12       Impact factor: 9.546
  7 in total

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