HPL and estriol serum levels of placental perfusion as indexes of placental function in EPH gestosis and placental insufficiency.

62 patients with EPH gestosis and 64 subjects suffering from placental insufficiency were monitored with estimation of placental perfusion and determination of radioimmunoassayable serum levels of human placental lactogen (HPL) and estriol. The utero-placental blood flow was measured by quick intravenous administration of 0.25-1.0 mCi of (113m)In, and the radioactivity uptake curve was evaluated by a computer program. Good correlation between perfusion type of serum levels of HPL and estriol was recorded. The present data combine to suggest that the recording of utero-placental blood flow is valuable aid in the diagnostic and prognostic evaluation of high-risk pregnancies.