Literature DB >> 7409413

[The determination of verapamil in maternal and fetal blood (author's transl)].

R Strigl, G Gastroph, H G Hege, P Döring, W Mehring.   

Abstract

During the late first stage of labor and during the second stage of labor seven women in labor received an intravenous infusion during 60-110 minutes of verapamil at 2 g/k/per minute. Immediately following delivery of the infant, maternal and cord blood was drawn and the verapamil level measured by gas chromatography. The serum levels in the maternal blood were from 5.4 to 33.6 ng/ml. (Mean value 19.3 +/- 3.3 ng/ml) and the cord blood concentrations were 4.3-17.8 ng/ml (Mean value 8.5 +/- 1.9 ng/ml). The mean fetal serum level of verapamil was 51.4% of the mean maternal value.

Entities:  

Mesh:

Substances:

Year:  1980        PMID: 7409413     DOI: 10.1055/s-2008-1037365

Source DB:  PubMed          Journal:  Geburtshilfe Frauenheilkd        ISSN: 0016-5751            Impact factor:   2.915


  4 in total

Review 1.  Adverse reactions to calcium antagonists.

Authors:  J G Lewis
Journal:  Drugs       Date:  1983-02       Impact factor: 9.546

Review 2.  Verapamil. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.

Authors:  D McTavish; E M Sorkin
Journal:  Drugs       Date:  1989-07       Impact factor: 9.546

3.  Effects of calcium channel blockers on the development of early rat postimplantation embryos in culture.

Authors:  G Stein; M K Srivastava; H J Merker; D Neubert
Journal:  Arch Toxicol       Date:  1990       Impact factor: 5.153

4.  Arrhythmia and structural abnormalities of the fetal heart.

Authors:  P A Stewart; H M Tonge; J W Wladimiroff
Journal:  Br Heart J       Date:  1983-12
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.