| Literature DB >> 7407589 |
E Stefanini, A M Marchisio, P Devoto, F Vernaleone, R Collu, P F Spano.
Abstract
Sulpiride and other benzamide (BM)-displacing activity on [3H]-spiroperidol ([3H]SPIR) binding by rat striatal dopaminergic receptors was found to be uniquely sodium-dependent, while classical neuroleptic (NL) activity was not influenced by NaCl. These results suggest the existence of at least two populations of striatal dopaminergic receptors, sodium-dependent and sodium-independent, through which BM and NL respectively interact.Entities:
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Year: 1980 PMID: 7407589 DOI: 10.1016/0006-8993(80)90360-1
Source DB: PubMed Journal: Brain Res ISSN: 0006-8993 Impact factor: 3.252