Literature DB >> 7407418

Participation of ADP in the binding of fibrinogen to thrombin-stimulated platelets.

E F Plow, G A Marguerie.   

Abstract

Thrombin and adenosine diphosphate (ADP) supported the binding of 125I-fibrinogen to washed human platelets with similar kinetics and affinity. Platelet secretion, as measured by 14C-serotonin release, and fibrinogen binding exhibited an identical dependence on thrombin concentration. Enzymatic removal of ADP with apyrase or creatine phosphate/creatine phosphokinase (CP/CPK) from thrombin-stimulated platelets markedly inhibited 125I-fibrinogen binding, but pretreatment of platelets with CP/CPK prior to thrombin stimulation was without effect. Thus, ADP, released from the platelet, participates in the binding of fibrinogen to thrombin-stimulated platelets.

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Year:  1980        PMID： 7407418

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  23 in total

1.  RGDfK-functionalized gold nanorods bind only to activated platelets.

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2.  Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon.

Authors:  S R Hanson; F I Pareti; Z M Ruggeri; U M Marzec; T J Kunicki; R R Montgomery; T S Zimmerman; L A Harker
Journal:  J Clin Invest       Date:  1988-01       Impact factor: 14.808

3.  Plasminogen interacts with human platelets through two distinct mechanisms.

Authors:  L A Miles; M H Ginsberg; J G White; E F Plow
Journal:  J Clin Invest       Date:  1986-06       Impact factor: 14.808

4.  Aggregation efficiency of activated normal or fixed platelets in a simple shear field: effect of shear and fibrinogen occupancy.

Authors:  Z Xia; M M Frojmovic
Journal:  Biophys J       Date:  1994-06       Impact factor: 4.033

5.  Monocytes and platelets share the glycoproteins IIb and IIIa that are absent from both cells in Glanzmann's thrombasthenia type I.

Authors:  G Gogstad; O Hetland; N O Solum; H Prydz
Journal:  Biochem J       Date:  1983-08-15       Impact factor: 3.857

6.  Complex formation of platelet thrombospondin with fibrinogen.

Authors:  L L Leung; R L Nachman
Journal:  J Clin Invest       Date:  1982-09       Impact factor: 14.808

7.  Inhibition of fibrinogen binding to human platelets by the tetrapeptide glycyl-L-prolyl-L-arginyl-L-proline.

Authors:  E F Plow; G Marguerie
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

8.  Effects of age, sex and the oral contraceptive on the platelet membrane fibrinogen binding site (glycoprotein IIb/IIIa).

Authors:  M Cahill; R Mistry; C Chapman; J K Wood; D B Barnett
Journal:  Br J Clin Pharmacol       Date:  1992-01       Impact factor: 4.335

Review 9.  Characteristics of an ADP receptor mediating platelet activation.

Authors:  R W Colman; W R Figures
Journal:  Mol Cell Biochem       Date:  1984       Impact factor: 3.396

10.  Spontaneous platelet aggregation in a hereditary giant platelet syndrome (MPS).

Authors:  J G Milton; M M Frojmovic; S S Tang; J G White
Journal:  Am J Pathol       Date:  1984-02       Impact factor: 4.307
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