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Literature DB >> 7406887

Selective uptake of cadmium by the parenchyumal cells of liver.

Abstract

The uptake of cadmium in vivo into parenchymal and non-parenchymal (sinusoidal) cells of the liver was studied by a cell-separation technique. Liver parenchymal cells accumulate cadmium more readily than do non-parenchymal cells and synthesize metallothionein. It is proposed that cadmium uptake and metabolism from injected CdCl2, is restricted almost exclusively to the liver parenchymal cells.

Entities: Chemical

Mesh：

Substances：
Cadmium
Metallothionein

Year: 1980 PMID： 7406887 PMCID： PMC1162567 DOI： 10.1042/bj1880285

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

13 in total

1. THE FATE OF CD109 IN THE MOUSE. AN AUTORADIOGRAPHIC STUDY AFTER A SINGLE INTRAVENOUS INJECTION OF CD109CL2.

Authors: M BERLIN; S ULLBERG
Journal: Arch Environ Health Date: 1963-12

2. Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion.

Authors: P O Seglen
Journal: Exp Cell Res Date: 1973-12 Impact factor: 3.905

3. Hypertension and tissue metal levels after intraperitoneal cadmium, mercury, and zinc.

Authors: H M Perry; M Erlanger
Journal: Am J Physiol Date: 1971-03

4. Isolation of a soluble cadmium-binding protein from pulmonary macrophages.

Authors: C C Cox; M D Waters
Journal: Toxicol Appl Pharmacol Date: 1978-11 Impact factor: 4.219

5. The uptake and subsequent loss of beryllium by rat liver parenchymal and non-parenchymal cells after the intravenous administration of particulate and soluble forms.

Authors: D N Skilleter; R J Price
Journal: Chem Biol Interact Date: 1978-03 Impact factor: 5.192

6. The effects of acute cadmium administration in the liver and kidney of the rat. Light and electron microscopic studies.

Authors: E O Hoffmann; J A Cook; N R di Luzio; J A Coover
Journal: Lab Invest Date: 1975-05 Impact factor: 5.662

7. Metallothionein degradation: metal composition as a controlling factor.

Authors: K Cain; D E Holt
Journal: Chem Biol Interact Date: 1979 Impact factor: 5.192

8. Zinc uptake by isolated rat liver parenchymal cells.

Authors: M L Failla; R J Cousins
Journal: Biochim Biophys Acta Date: 1978-02-01

9. Distribution of organelles and membranes between hepatocytes and nonhepatocytes in the rat liver parenchyma. A stereological study.

Authors: A Blouin; R P Bolender; E R Weibel
Journal: J Cell Biol Date: 1977-02 Impact factor: 10.539

7. Analysis of the effects of overexpression of metallothionein-I in transgenic mice on the reproductive toxicology of cadmium.

Authors: T Dalton; K Fu; G C Enders; R D Palmiter; G K Andrews
Journal: Environ Health Perspect Date: 1996-01 Impact factor: 9.031

7 in total

Selective uptake of cadmium by the parenchyumal cells of liver.

1. THE FATE OF CD109 IN THE MOUSE. AN AUTORADIOGRAPHIC STUDY AFTER A SINGLE INTRAVENOUS INJECTION OF CD109CL2.

2. Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion.

3. Hypertension and tissue metal levels after intraperitoneal cadmium, mercury, and zinc.

4. Isolation of a soluble cadmium-binding protein from pulmonary macrophages.

5. The uptake and subsequent loss of beryllium by rat liver parenchymal and non-parenchymal cells after the intravenous administration of particulate and soluble forms.

6. The effects of acute cadmium administration in the liver and kidney of the rat. Light and electron microscopic studies.

7. Metallothionein degradation: metal composition as a controlling factor.

8. Zinc uptake by isolated rat liver parenchymal cells.

9. Distribution of organelles and membranes between hepatocytes and nonhepatocytes in the rat liver parenchyma. A stereological study.

10. Acute effects of cadmium on the pregnant rat and embryo-fetal development.

1. The fate of Cd, Cu, Ca, Zn, and Fe in rat during the recovery period following cessation of repeated exposure to Cd.

2. Comparison of cadmium-metallothionein synthesis in parenchymal and non-parenchymal rat liver cells.

3. Identification of metallothionein in parenchymal and non-parenchymal liver cells of the adult rat.

4. Cadmium-induced hepatotoxicity in cultured rat hepatocytes as evaluated by morphometric analysis.

5. Cadmium metabolism by rat liver endothelial and Kupffer cells.

6. The ultrastructural localization of metallothionein in cadmium exposed rat liver.

7. Analysis of the effects of overexpression of metallothionein-I in transgenic mice on the reproductive toxicology of cadmium.