Literature DB >> 740598

Induction of spermatogenesis in hypogonadotrophic hypogonadism.

I M Spitz, Z Schumert, J Steiner, E Rosen, S Segal, A Slonim, D Rabinowitz.   

Abstract

A young male who presented with isolated bihormonal gonadotrophin deficiency is described, Basal levels of LH and FSH were low and there was no response to clomiphene citrate or LHRH. The remaining anterior pituitary function was intact. The administration of a combination of human menopausal gonadotrophin and human chorionic gonadotrophin caused testicular maturation with spermatogenesis and full androgenization. The patient was able to father a child.

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Year:  1978        PMID: 740598      PMCID: PMC2425082          DOI: 10.1136/pgmj.54.636.694

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  12 in total

Review 1.  Isolated gonadotropin deficiency and related disorders.

Authors:  D Rabinowitz; I M Spitz
Journal:  Isr J Med Sci       Date:  1975-10

2.  Olfactory status and response to clomiphene in male gonadotrophin deficiency.

Authors:  C R Hamilton; R I Henkin; G Weir; B Kliman
Journal:  Ann Intern Med       Date:  1973-01       Impact factor: 25.391

3.  Gonadotrophin-releasing hormone therapy in hypogonadal males with hypothalamic or pituitary dysfunction.

Authors:  C H Mortimer; A S McNeilly; R A Fisher; M A Murray; G M Besser
Journal:  Br Med J       Date:  1974-12-14

4.  Serum LH and FSH responses to the repetitive administration of gonadotropin-releasing hormone in patients with idiopathic hypogonadotropic hypogonadism.

Authors:  J F Reitano; R Caminos-Torres; P J Snyder
Journal:  J Clin Endocrinol Metab       Date:  1975-12       Impact factor: 5.958

5.  Comparison of short and long-term treatment with synthetic LH-releasing hormone and clomiphene citrate in male hypothalamic hypogonadism.

Authors:  T Hashimoto; K Miyai; T Onishi; K Matsumoto; Y Kumahara
Journal:  J Clin Endocrinol Metab       Date:  1975-11       Impact factor: 5.958

6.  Hypothalamic follicle-stimulating hormone (FSH) and luteinizing hormone (LH)-regulating hormone: structure, physiology, and clinical studies.

Authors:  A V Schally; A J Kastin; A Arimura
Journal:  Fertil Steril       Date:  1971-11       Impact factor: 7.329

7.  Restoration of normal pituitary gonadotropin reserve by administration of luteinizing-hormone-releasing hormone in patients with hypogonadotropic hypogonadism.

Authors:  Y Yoshimoto; K Moridera; H Imura
Journal:  N Engl J Med       Date:  1975-01-30       Impact factor: 91.245

8.  Heterogeneity of prolactin and TSH response to TRH in hypotonadotropic hypogonadism.

Authors:  T Yamaji; K Shimamoto; K Kosaka; K Isurugi
Journal:  J Clin Endocrinol Metab       Date:  1977-08       Impact factor: 5.958

9.  FSH and LH response to luteinizing hormone-releasing factor in prepubertal and pubertal children, adult males and patients with hypogonadotropic and hypertropic hypogonadism.

Authors:  J C Roth; R P Kelch; S L Kaplan; M M Grumbach
Journal:  J Clin Endocrinol Metab       Date:  1972-12       Impact factor: 5.958

10.  Effectf of synthetic luteinizing hormone-releasing hormone (LH-RH) in two brothers with hypogonadotropic hypogonadism and anosmia.

Authors:  A Zárate; A J Kastin; J Soria; E S Canales; A V Schally
Journal:  J Clin Endocrinol Metab       Date:  1973-03       Impact factor: 5.958

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  1 in total

1.  Induction of spermatogenesis in isolated hypogonadotropic hypogonadism with exogenous human chorionic gonadotropin.

Authors:  R Luboshitzky; G Dickstein; D Barzilai
Journal:  J Endocrinol Invest       Date:  1981 Apr-Jun       Impact factor: 4.256

  1 in total

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