Literature DB >> 7403880

Human cutaneous lieshmania in a mouse macrophage line: propagation and isolation of intracellular parasites.

K P Chang.   

Abstract

A mouse macrophage line, J774G8, supports continuous and prolific intracellular growth of Leishmania mexicana amazonensis, the etiological agent of a South American cutaneous leishmaniasis. The intracellular parasites from these infected cultures can be isolated with high recovery rate and purity by simple Percoll gradient centrifugation.

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Year:  1980        PMID： 7403880     DOI： 10.1126/science.7403880

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  61 in total

1.  Episomal expression of specific sense and antisense mRNAs in Leishmania amazonensis: modulation of gp63 level in promastigotes and their infection of macrophages in vitro.

Authors:  D Q Chen; B K Kolli; N Yadava; H G Lu; A Gilman-Sachs; D A Peterson; K P Chang
Journal:  Infect Immun       Date:  2000-01       Impact factor: 3.441

2.  N-terminal fatty acid substitution increases the leishmanicidal activity of CA(1-7)M(2-9), a cecropin-melittin hybrid peptide.

Authors:  C Chicharro; C Granata; R Lozano; D Andreu; L Rivas
Journal:  Antimicrob Agents Chemother       Date:  2001-09       Impact factor: 5.191

3.  A new experimental culture medium for cultivation of Leishmania amazonensis: its efficacy for the continuous in vitro growth and differentiation of infective promastigote forms.

Authors:  Igor de Almeida Rodrigues; Bianca Alcântara da Silva; André Luis Souza dos Santos; Alane Beatriz Vermelho; Celuta Sales Alviano; Patrícia Maria Lourenço Dutra; Maria do Socorro Santos Rosa
Journal:  Parasitol Res       Date:  2010-02-23       Impact factor: 2.289

4.  Leishmania mexicana amazonensis: plasma membrane adenine nucleotide translocator and chemotaxis.

Authors:  S Detke; R Elsabrouty
Journal:  Exp Parasitol       Date:  2007-10-22       Impact factor: 2.011

5.  An axenic amastigote system for drug screening.

Authors:  H L Callahan; A C Portal; R Devereaux; M Grogl
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191

6.  3'-Deoxy-3'-fluoroinosine as a potent antileishmanial agent. The metabolism and selective cytotoxic effect of 3'-deoxy-3'-fluoroinosine against Leishmania tropica and L. donovani in vitro and in vivo.

Authors:  I S Shin; H Tanifuji; Y Arata; Y Morizawa; T Nakayama; Y Wataya
Journal:  Parasitol Res       Date:  1995       Impact factor: 2.289

7.  Tubulin biosynthesis in the developmental cycle of a parasitic protozoan, Leishmania mexicana: changes during differentiation of motile and nonmotile stages.

Authors:  D Fong; K P Chang
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

8.  Interaction of Leishmania donovani promastigotes with human monocyte-derived macrophages: parasite entry, intracellular survival, and multiplication.

Authors:  R D Pearson; R Romito; P H Symes; J L Harcus
Journal:  Infect Immun       Date:  1981-06       Impact factor: 3.441

9.  Design of protease-resistant pexiganan enhances antileishmanial activity.

Authors:  Manjusha M Kulkarni; Anna Karafova; Wojciech Kamysz; Bradford S McGwire
Journal:  Parasitol Res       Date:  2014-05       Impact factor: 2.289

10.  Leishmania donovani depletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth.

Authors:  Nupur Kanti Das; Sudipta Biswas; Sunil Solanki; Chinmay K Mukhopadhyay
Journal:  Cell Microbiol       Date:  2008-09-24       Impact factor: 3.715
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