Literature DB >> 7400877

The breakdown of collagen by chondrocytes.

R W Jubb, H B Fell.   

Abstract

The chondrocytes of pure articular cartilage from young pigs display collagenolytic activity when the cartilage is cultivated by an organ culture method in medium containing 5--10 IU retinol/ml. Breakdown of collagen occurs in all regions of the cartilage; in the thicker explants it is greatest and most frequent in those that contain the deepest zone composed of proliferating and hypertrophic chondrocytes; it is also very drastic in thin explants composed mainly of superficial fibro-cartilage.

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Year:  1980        PMID: 7400877     DOI: 10.1002/path.1711300304

Source DB:  PubMed          Journal:  J Pathol        ISSN: 0022-3417            Impact factor:   7.996


  30 in total

1.  Honor Bridgett Fell, Ph.D., D.Sc. F.R.S., D.B.E., 1900-1986. The scientist and her contributions.

Authors:  A R Poole
Journal:  In Vitro Cell Dev Biol       Date:  1989-05

2.  Assessment of the clinical significance of gelatinase activity in patients with juvenile idiopathic arthritis using quantitative protein substrate zymography.

Authors:  N J Peake; H E Foster; K Khawaja; T E Cawston; A D Rowan
Journal:  Ann Rheum Dis       Date:  2005-09-08       Impact factor: 19.103

3.  TIMP-2 is required for efficient activation of proMMP-2 in vivo.

Authors:  Z Wang; R Juttermann; P D Soloway
Journal:  J Biol Chem       Date:  2000-08-25       Impact factor: 5.157

4.  Interleukin 13 blocks the release of collagen from bovine nasal cartilage treated with proinflammatory cytokines.

Authors:  C S Cleaver; A D Rowan; T E Cawston
Journal:  Ann Rheum Dis       Date:  2001-02       Impact factor: 19.103

5.  Esculetin inhibits cartilage resorption induced by interleukin 1alpha in combination with oncostatin M.

Authors:  S Elliott; A D Rowan; S Carrère; P Koshy; J B Catterall; T E Cawston
Journal:  Ann Rheum Dis       Date:  2001-02       Impact factor: 19.103

6.  Xanthene-dye-labelled phosphatidylethanolamines as probes of interfacial pH. Studies in phospholipid vesicles.

Authors:  C G Knight; T Stephens
Journal:  Biochem J       Date:  1989-03-15       Impact factor: 3.857

7.  Treatment with SiMiaoFang, an anti-arthritis chinese herbal formula, inhibits cartilage matrix degradation in osteoarthritis rat model.

Authors:  Ying Xu; Qian Liu; Zhen-Li Liu; Li Lim; Wei-Heng Chen; Na Lin
Journal:  Rejuvenation Res       Date:  2013-10       Impact factor: 4.663

8.  Matrix depletion of young and old human articular cartilage by cultured autologous synovium fragments: a chondrocyte-independent effect.

Authors:  A A Dogterom; O Huber-Bruning; J E Vernooy; B Wilbrink; W den Otter; J Huber
Journal:  Rheumatol Int       Date:  1985       Impact factor: 2.631

9.  The production in culture of metalloproteinases and an inhibitor by joint tissues from normal rabbits, and from rabbits with a model arthritis. II. Articular cartilage.

Authors:  G Murphy; G J Cambray; N Virani; D P Page-Thomas; J J Reynolds
Journal:  Rheumatol Int       Date:  1981       Impact factor: 2.631

10.  Adenoviral gene transfer of interleukin-1 in combination with oncostatin M induces significant joint damage in a murine model.

Authors:  Andrew D Rowan; Wang Hui; Tim E Cawston; Carl D Richards
Journal:  Am J Pathol       Date:  2003-06       Impact factor: 4.307

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