Literature DB >> 7399669

Identification of staphylococcal Panton-Valentine leukocidin as a potent dermonecrotic toxin.

P D Ward, W H Turner.   

Abstract

The Panton-Valentine leukocidin of Staphylococcus aureus was shown to exhibit a potent dermonecrotic effect when injected intradermally into rabbits. This effect could be abrogated by immunizing animals with the F component or both components, but immunization with the S component appeared to exacerbate certain of the intradermal responses.

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Year:  1980        PMID: 7399669      PMCID: PMC550947          DOI: 10.1128/iai.28.2.393-397.1980

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  11 in total

1.  Assay of the two components of staphylococcal leucocidin and their antibodies.

Authors:  A M WOODIN
Journal:  J Pathol Bacteriol       Date:  1961-01

2.  A simple method for the detection of lipolytic activity of micro-organisms and some observations on the influence of the contact between cells and fatty substrates.

Authors:  G SIERRA
Journal:  Antonie Van Leeuwenhoek       Date:  1957       Impact factor: 2.271

3.  A study of the necrotizing action of staphylococcic alpha toxin.

Authors:  R W BROWN; R K SCHERER
Journal:  Am J Vet Res       Date:  1958-04       Impact factor: 1.156

4.  Studies in hospital infections. I.

Authors:  J C COLBECK
Journal:  Can Serv Med J       Date:  1956 Jul-Aug

5.  Purification and properties of staphylococcal delta hemolysin.

Authors:  A S Kreger; K S Kim; F Zaboretzky; A W Bernheimer
Journal:  Infect Immun       Date:  1971-03       Impact factor: 3.441

6.  Natural and experimental staphylococcal mastitis in rabbits.

Authors:  C Adlam; C M Thorley; P D Ward; M Collins; R N Lucken; P A Knight
Journal:  J Comp Pathol       Date:  1976-10       Impact factor: 1.311

7.  Studies on extracellular proteins from Staphylococcus aureus. VII. Studies on -haemolysin.

Authors:  T Wadström; R Möllby
Journal:  Biochim Biophys Acta       Date:  1971-07-21

8.  A histopathological study of the effects of highly purified staphlococcal alpha and beta toxins on the lactating mammary gland and skin of the rabbit.

Authors:  P D Ward; C Adlam; A C McCartney; J P Arbuthnott; C M Thorley
Journal:  J Comp Pathol       Date:  1979-04       Impact factor: 1.311

9.  Isolation of mutants of Staphylococcus aureus lacking extracellular nuclease activity.

Authors:  G S Omenn; J Friedman
Journal:  J Bacteriol       Date:  1970-03       Impact factor: 3.490

10.  Subcutaneous staphylococcal infection in mice. I. The role of cotton-dust in enhancing infection.

Authors:  D S Agarwal
Journal:  Br J Exp Pathol       Date:  1967-08
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  30 in total

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Review 2.  Role of pore-forming toxins in bacterial infectious diseases.

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4.  Genetic characterization of Panton-Valentine leukocidin-producing methicillin-resistant Staphylococcus aureus in Western Austria.

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5.  Frequent carriage of Panton-Valentine leucocidin genes by Staphylococcus aureus isolates from surgically drained abscesses.

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6.  Structure-based discovery of a small-molecule inhibitor of methicillin-resistant Staphylococcus aureus virulence.

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7.  Short communication: methicillin-resistant Staphylococcus aureus infections in children and young adults infected with HIV.

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8.  Panton-Valentine leucocidin and gamma-hemolysin from Staphylococcus aureus ATCC 49775 are encoded by distinct genetic loci and have different biological activities.

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Journal:  Infect Immun       Date:  1995-10       Impact factor: 3.441

Review 9.  The role of virulence determinants in community-associated MRSA pathogenesis.

Authors:  Binh An Diep; Michael Otto
Journal:  Trends Microbiol       Date:  2008-06-26       Impact factor: 17.079

10.  Characteristics of Staphylococcus aureus infections, Chicago Pediatric Hospital.

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