Literature DB >> 7398852

Effect of praseodymium on drug metabolism in rat liver smooth and rough endoplasmic reticulum.

P Arvela, B von Lehmann, O Grajewski, E Oberdisse.   

Abstract

A small i.v. dose (3 mg/kg) of a light lanthanon, praseodymium, impairs the drug metabolizing capacity of both the smooth and rough fractions of rat liver endoplasmic reticulum. This decrease in the activity of drug metabolizing enzymes and in the amount of cytochromes P-450 and b5 is more pronounced in the rough endoplasmic reticulum fraction.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7398852     DOI： 10.1007/bf01978615

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE.

Authors:  T OMURA; R SATO
Journal:  J Biol Chem       Date:  1964-07       Impact factor: 5.157

2.  THE BEHAVIOR OF CERTAIN LANTHANONS IN RATS.

Authors:  G MAGNUSSON
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1963

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Metabolism of drugs and carcinogens by human liver enzymes.

Authors:  R Kuntzman; L C Mark; L C Brand; B M Jacobson; W Levin; A H Conney
Journal:  J Pharmacol Exp Ther       Date:  1966-04       Impact factor: 4.030

5.  Subcellular fractionation of rat liver.

Authors:  S Fleischer; M Kervina
Journal:  Methods Enzymol       Date:  1974       Impact factor: 1.600

6.  The effect of phenobarbital pretreatment on the cerium induced impairment of drug metabolism in rat.

Authors:  P Arvela; N T Kärki
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1972

7.  Functional components of the liver microsomal enzyme system catalysing fatty acid, hydrocarbon and drug hydroxylation.

Authors:  M J Coon; H W Strobel; A P Autor; J Heidema; W Duppel
Journal:  Biochem J       Date:  1971-11       Impact factor: 3.857
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.