Literature DB >> 7398678

Species variation in the metabolism of 1-naphthylacetylglycylglycylglycine.

P A Dixon.   

Abstract

1-Naphthylacetylglycylglycylglycine was metabolized in rat and rabbit to mainly 1-naphthylacetylglucuronide; in toad to 1-naphthylacetic acid and 1-naphtylacetylglycine, and in lizard and tortoise to 1-naphthylacetic acid and its glycine and ornithine conjugates. In the in vitro studies, varying amounts of 1-naphthylacetic acid, its glycine and glycylglycine conjugates and some of the unchanged compound were detected in all the species.

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Year:  1980        PMID： 7398678     DOI： 10.1007/BF03189447

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN： 0378-7966            Impact factor:   2.441


  7 in total

1.  Studies in detoxication. 82. The fate of benzoic acid in some domestic and other birds.

Authors:  B C BALDWIN; D ROBINSON; R T WILLIAMS
Journal:  Biochem J       Date:  1960-09       Impact factor: 3.857

2.  Cleavage of active peptides by a lung enzyme.

Authors:  R Igic; H S Yeh; K Sorrells; E G Erdos
Journal:  Experientia       Date:  1972-02-15

3.  Concentrations of angiotensin-converting enzyme in tissues of the rat.

Authors:  D W Cushman; H S Cheung
Journal:  Biochim Biophys Acta       Date:  1971-10

4.  Studies on the angiotensin converting enzyme with different substrates.

Authors:  Y Piquilloud; A Reinharz; M Roth
Journal:  Biochim Biophys Acta       Date:  1970-04-22

5.  An enzyme in microsomal fraction of kidney that inactivates bradykinin.

Authors:  E G Erdos; H Y Yang
Journal:  Life Sci       Date:  1967-03-15       Impact factor: 5.037

6.  Metabolism of arylacetic acids. 1. The fate of 1-naphthylacetic acid and its variation with species and dose.

Authors:  P A Dixon; J Caldwell; R L Smith
Journal:  Xenobiotica       Date:  1977-11       Impact factor: 1.908

7.  Metabolism of ( 14 C)methamphetamine in man, the guinea pig and the rat.

Authors:  J Caldwell; L G Dring; R T Williams
Journal:  Biochem J       Date:  1972-08       Impact factor: 3.857
  7 in total

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