Atenolol 4% eyedrops in glaucoma simplex.

The single-dose response to local administration of atenolol 4% is compared in normal eyes and 3 groups of eyes with glaucoma simplex. The reduction in intraocular pressure is seen to be greater in eyes with glaucoma than in normal eyes. The usefulness of atenolol 4%, whether or not combined with other local therapy, seems to be limited by tachyphylaxis.