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Literature DB >> 7398394

Interaction of rifampin and chlorpropamide.

Abstract

A 62-year-old man who had been taking 250 mg of chlorpropamide daily for several years received rifampin concomitantly and had a subsequent increased dosing requirement of chlorpropamide. When rifampin was discontinued several months later, the serum chlorpropamide concentration rose dramatically.

Entities: Chemical Species

Mesh：

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Year: 1980 PMID： 7398394 DOI： 10.1378/chest.77.6.800

Source DB: PubMed Journal: Chest ISSN： 0012-3692 Impact factor: 9.410

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Cited

8 in total

Review 1. Drug interactions that matter. A critical reappraisal.

Authors: G T McInnes; M J Brodie
Journal: Drugs Date: 1988-07 Impact factor: 9.546

Review 2. Clinically significant interactions with drugs used in the treatment of tuberculosis.

Authors: W W Yew
Journal: Drug Saf Date: 2002 Impact factor: 5.606

3. Pharmacokinetics of chlorpropamide in epileptic patients: effects of enzyme induction and urine pH on chlorpropamide elimination.

Authors: P J Neuvonen; S Kärkkäinen; R Lehtovaara
Journal: Eur J Clin Pharmacol Date: 1987 Impact factor: 2.953

Review 4. Pharmacokinetic drug interactions with rifampicin.

Authors: K Venkatesan
Journal: Clin Pharmacokinet Date: 1992-01 Impact factor: 6.447

5. Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.

Authors: Ji-Hong Shon; Young-Ran Yoon; Min-Jung Kim; Kyoung-Ah Kim; Young-Chae Lim; Kwang-Hyeon Liu; Dong-Hoon Shin; Chung Han Lee; In-June Cha; Jae-Gook Shin
Journal: Br J Clin Pharmacol Date: 2005-05 Impact factor: 4.335

Interaction of rifampin and chlorpropamide.

Review 1. Drug interactions that matter. A critical reappraisal.

Review 2. Clinically significant interactions with drugs used in the treatment of tuberculosis.

3. Pharmacokinetics of chlorpropamide in epileptic patients: effects of enzyme induction and urine pH on chlorpropamide elimination.

Review 4. Pharmacokinetic drug interactions with rifampicin.

5. Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.

Review 6. Clinical pharmacokinetics of the antituberculosis drugs.

Review 7. Antihyperglycaemic agents. Drug interactions of clinical importance.

Review 8. Pharmacokinetic-pharmacodynamic relationships of oral hypoglycaemic agents. An update.