| Literature DB >> 7397064 |
R Ellul-Micallef, R C Borthwick, G J McHardy.
Abstract
Patients with bronchial asthma frequently have a fall in arterial oxygen tension following bronchodilator treatment in spite of a reduction in airway resistance. Administration of 0.11 mM (40 mg) prednisolone in a single dose resulted in an improvement of both airway obstruction and hypoxaemia in chronic asthmatic patients. The arterial oxygen tension, alveolar-arterial oxygen tension difference and venous admixture effect all showed a statistically significant improvement as did the dynamic lung volumes and specific airway conductance.Entities:
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Year: 1980 PMID: 7397064 PMCID: PMC1429940 DOI: 10.1111/j.1365-2125.1980.tb05843.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN: 0306-5251 Impact factor: 4.335