Literature DB >> 7396831

Identification of O-acetyl-5-methoxytryptophenol in the pineal gland by gas chromatography-mass spectrometry.

I Smith, P Francis, R M Leone, P E Mullen.   

Abstract

The presence of O-acetyl-5-methoxytryptophol in the pineal glands of rats kept in the dark for 8 h, but not in the light, has been shown by means of g.l.c.-mass spectrometry. It is suggested that this compound may be the biologically active precursor of circulating methoxytryptophol.

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Year:  1980        PMID： 7396831      PMCID： PMC1161385          DOI： 10.1042/bj1850537

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  6 in total

1.  Age-dependent effects of 5-methoxytryptophol and melatonin on testes and comb growth of the white leghorn (Gallus domesticus L.).

Authors:  M G Balemans
Journal:  J Neural Transm       Date:  1972       Impact factor: 3.575

2.  The influence of 5-methoxytryptophol, a pineal compound, on comb growth, ovarian weight, follicular growth and egg production of juvenile, maturing and adult white leghorn hens (Gallus domesticus L.).

Authors:  M G Balemans; F C van de Veerdonk; J C van de Kamer
Journal:  J Neural Transm       Date:  1977       Impact factor: 3.575

3.  Inhibition of human chorionic gonadotrophin-induced hypertrophy of the ovaries and uterus in immature mice by some pineal indoles, 6-hydroxymelatonin and arginine vasotocin.

Authors:  M K Vaughan; G M Vaughan; R J Reiter
Journal:  J Endocrinol       Date:  1976-03       Impact factor: 4.286

4.  A sensitive and specific assay for 5-methoxytryptophol in plasma.

Authors:  R M Leone; R E Silman; R J Hooper; M D Finnie; S J Carter; R Edwards; I Smith; P Towell; P E Mullen
Journal:  J Endocrinol       Date:  1979-08       Impact factor: 4.286

5.  Changes in the concentration of 5-methoxytryptophol in the circulation at different phases of the human menstrual cycle.

Authors:  R J Hooper; R E Silman; R M Leone; M D Finnie; S J Carter; J G Grudzinskas; Y B Gordon; D T Holland; T Chard; P E Mullen; I Smith
Journal:  J Endocrinol       Date:  1979-08       Impact factor: 4.286

6.  The inhibitory effect of 5-methoxytryptophol on ovarian weight, follicular growth and egg production of adult white leghorn hens (Gallus domesticus L.).

Authors:  M G Balemans
Journal:  J Neural Transm       Date:  1973       Impact factor: 3.575
  6 in total
  7 in total

1.  Effects of afternoon injections of O-acetyl-5-methoxytryptophol, melatonin or 5-methoxytryptophol in female Syrian hamsters.

Authors:  J C Little; M K Vaughan; N Haider; I Smith; R J Reiter
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

2.  Natural and synthetic analogues of melatonin and related compounds. I. Effects on the reproductive system of the male Syrian hamster.

Authors:  B A Richardson; M K Vaughan; L J Petterborg; L Y Johnson; T S King; I Smith; R J Reiter
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

3.  Acyltryptophols reversibly inhibit the uptake of thymidine after phytohaemagglutinin transformation of human lymphocytes.

Authors:  A Moshtaghfard; I Smith
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

4.  Acyltryptophols reversibly inhibit muscle contractions caused by the actions of acetylcholine and raised potassium ion concentrations.

Authors:  I N Fernando; P L Francis; I Smith
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

5.  5-Methoxyindoles in pineal gland of cow, pig, sheep and rat.

Authors:  O Beck; G Jonsson; A Lundman
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-12       Impact factor: 3.000

6.  Changes in the circadian rhythmicity of N- and O-acetyltransferase activities in the pineal gland of 38 day old male wistar rats when examined under white, red and green light.

Authors:  M G Balemans; I Smith; G F de Reuver
Journal:  J Neural Transm       Date:  1981       Impact factor: 3.575

7.  Melatonin metabolism in the central nervous system.

Authors:  Rüdiger Hardeland
Journal:  Curr Neuropharmacol       Date:  2010-09       Impact factor: 7.363
  7 in total

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