Literature DB >> 7396715

Detection of tetrodotoxin in autopsy material by gas chromatography.

K Suenaga, S Kotoku.   

Abstract

A gas chromatographic method for the detection of tetrodotoxin in autopsy material is described. The derivative (2-amino-6-hydroxymethyl-8-hydroxyquinazoline, C9-base), which was obtained from tetrodotoxin by alkali treatment, was finally detected by gas chromatography. The mass spectra of the trimethysilylated ( TMS) C9-base are presented together with the result of a gas chromatographic investigation of 8 cases of fatal intoxication.

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Year:  1980        PMID: 7396715     DOI: 10.1007/bf00278036

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN: 0340-5761            Impact factor:   5.153


  8 in total

1.  TARICHATOXIN--TETRODOTOXIN: A POTENT NEUROTOXIN.

Authors:  H S MOSHER; F A FUHRMAN; H D BUCHWALD; H G FISCHER
Journal:  Science       Date:  1964-05-29       Impact factor: 47.728

2.  A fluorimetric method to determine tetrodotoxin.

Authors:  M T Nuñez; S Fischer; E Jaimovich
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

3.  A convenient bioassay for detecting nanomolar concentrations of tetrodotoxin.

Authors:  P N Strong; J T Smith; J F Keana
Journal:  Toxicon       Date:  1973-08       Impact factor: 3.033

Review 4.  Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena.

Authors:  C Y Kao
Journal:  Pharmacol Rev       Date:  1966-06       Impact factor: 25.468

5.  Tetrodotoxin.

Authors:  T Goto; Y Kishi; S Takahashi; Y Hirata
Journal:  Tetrahedron       Date:  1965-08       Impact factor: 2.457

6.  Tetrodotoxin. It is a powerful poison that is found in two almost totally unrelated kinds of animal: puffer fish and newts. It has been serving as a tool in nerve physiology and may provide a model for new local anesthetics.

Authors:  F A Fuhrman
Journal:  Sci Am       Date:  1967-08       Impact factor: 2.142

7.  An upper limit to the number of sodium channels in nerve membrane?

Authors:  J W Moore; T Narahashi; T I Shaw
Journal:  J Physiol       Date:  1967-01       Impact factor: 5.182

8.  Tetrodotoxin. VII. On the structure of tetrodotoxin and its derivatives.

Authors:  K Tsuda; S Ikuma; M Kawamura; R Tachikawa; K Sakai
Journal:  Chem Pharm Bull (Tokyo)       Date:  1964-11       Impact factor: 1.645

  8 in total
  4 in total

1.  Reexamination of tetrodotoxin production by bacteria.

Authors:  K Matsumura
Journal:  Appl Environ Microbiol       Date:  1995-09       Impact factor: 4.792

Review 2.  Potential Threats Posed by Tetrodotoxins in UK Waters: Examination of Detection Methodology Used in Their Control.

Authors:  Andrew D Turner; Cowan Higgins; Wendy Higman; James Hungerford
Journal:  Mar Drugs       Date:  2015-12-11       Impact factor: 5.118

Review 3.  A review of chemical defense in harlequin toads (Bufonidae: Atelopus).

Authors:  Kannon C Pearson; Rebecca D Tarvin
Journal:  Toxicon X       Date:  2022-01-22

Review 4.  Tetrodotoxin--distribution and accumulation in aquatic organisms, and cases of human intoxication.

Authors:  Tamao Noguchi; Osamu Arakawa
Journal:  Mar Drugs       Date:  2008-05-28       Impact factor: 5.118

  4 in total

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