Literature DB >> 7395634

Multinucleation and polyploidization of aging human cells in culture.

T Matsumura.   

Abstract

In conclusion, evidence has been presented to show that multinucleation and polyploidization are common, if not ubiquitous, phenomena observable both in proliferating human cell populations in culture, and in cell populations which have already passed through their proliferative phase in culture. A hypothetical model is presented, the essence of which postulates the existence of a regularly controlled cell life, including DNA synthesis, out of cell cycle.

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Year:  1980        PMID: 7395634     DOI: 10.1007/978-1-4684-3734-8_4

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  5 in total

1.  Reproducibility: changing the policies and culture of cell line authentication.

Authors:  Leonard P Freedman; Mark C Gibson; Stephen P Ethier; Howard R Soule; Richard M Neve; Yvonne A Reid
Journal:  Nat Methods       Date:  2015-06       Impact factor: 28.547

2.  The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence.

Authors:  Wanyu L Lambiv; Irene Vassallo; Mauro Delorenzi; Tal Shay; Annie-Claire Diserens; Anjan Misra; Burt Feuerstein; Anastasia Murat; Eugenia Migliavacca; Marie-France Hamou; Davide Sciuscio; Raphael Burger; Eytan Domany; Roger Stupp; Monika E Hegi
Journal:  Neuro Oncol       Date:  2011-06-03       Impact factor: 12.300

3.  The out-of-field dose in radiation therapy induces delayed tumorigenesis by senescence evasion.

Authors:  Erwan Goy; Maxime Tomezak; Caterina Facchin; Nathalie Martin; Emmanuel Bouchaert; Jerome Benoit; Clementine de Schutter; Joe Nassour; Laure Saas; Claire Drullion; Priscille M Brodin; Alexandre Vandeputte; Olivier Molendi-Coste; Laurent Pineau; Gautier Goormachtigh; Olivier Pluquet; Albin Pourtier; Fabrizio Cleri; Eric Lartigau; Nicolas Penel; Corinne Abbadie
Journal:  Elife       Date:  2022-03-18       Impact factor: 8.140

4.  Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts.

Authors:  Suzana Makpol; Azalina Zainuddin; Kien Hui Chua; Yasmin Anum Mohd Yusof; Wan Zurinah Wan Ngah
Journal:  Clinics (Sao Paulo)       Date:  2012       Impact factor: 2.365

5.  Collagenase-resistant collagen promotes mouse aging and vascular cell senescence.

Authors:  Faran Vafaie; Hao Yin; Caroline O'Neil; Zengxuan Nong; Alanna Watson; John-Michael Arpino; Michael W A Chu; David Wayne Holdsworth; Robert Gros; J Geoffrey Pickering
Journal:  Aging Cell       Date:  2013-09-19       Impact factor: 9.304

  5 in total

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