Literature DB >> 7393224

Detection of an enzyme activity which cleaves m7 guanine from m7 GMP in an extract of embryonic chick lens cells.

G Gang, G C Lavers.   

Abstract

m7Guanine was cleaved from m7GMP by cytoplasmic enzyme activity in an extract prepared from embryonic chick lens cells. The appearance of m7-Guanine was proportional to the time and concentration of extract. m7-Guanine inhibited the reaction but neither guanine nor ribose 5-phosphate did. m7Guanine was not released from m7Guanosine. m7Guanine may be derived from m7GpppG mRNA cap by two enzymatic reactions with m7CMP as a product-substrate intermediate.

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Year:  1980        PMID： 7393224     DOI： 10.1007/bf00775752

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  6 in total

1.  Differential synthesis of lens proteins in the presence of m7G(5')pppG and cleavage product m7GMP in an embryonic chick lens cell lysate.

Authors:  G C Lavers
Journal:  Mol Biol Rep       Date:  1979-02-15       Impact factor: 2.316

2.  Metabolism of m7GMP-containing 5'terminal mRNA cap sequences in extracts of embryonic chick lens cells.

Authors:  G C Lavers
Journal:  Exp Eye Res       Date:  1979-03       Impact factor: 3.467

3.  Detection of methyltransferase activities which modify Gppp G to m7GpppGm in embryonic chick lens.

Authors:  G C Lavers
Journal:  Mol Biol Rep       Date:  1977-06       Impact factor: 2.316

4.  Synthesis and chemical properties of monomers and polymers containing 7-methylguanine and an investigation of their substrate or template properties for bacterial deoxyribonucleic acid or ribonucleic acid polymerases.

Authors:  S Hendler; E Fürer; P R Srinivasan
Journal:  Biochemistry       Date:  1970-10-13       Impact factor: 3.162

Review 5.  Chemistry of guanine and its biologically significant derivatives.

Authors:  R Shapiro
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1968

6.  Cleavage of pm7G from mRNA 5' terminal cap structures by pyrophosphatase activity in embryonic chick lens cells.

Authors:  G C Lavers
Journal:  Mol Biol Rep       Date:  1977-12       Impact factor: 2.316
  6 in total

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