| Literature DB >> 7392542 |
G Hess, W Arnold, K H Meyer zum Buschenfelde.
Abstract
The Dane particle is-because of its characteristics--believed to be the complete hepatitis-B-virus. Sera containing high numbers of Dane particles were shown to be highly infectious. In the present study we related the HBeAg-, the HBsAg- and the anti-HBc titer to the level of DNA polymerase activity measured in 20 fold Dane particle concentrates. The data obtained indicate that the HBeAg concentration gives a semiquantitative estimate on the number of circulating Dane particles. Mean DNA polymerase activity was found to increase with HBsAg concentration and is therefore also of value-if determined in a HBeAg positive serum- for quantitation of Dane particles. The anti-HBc titer was found to be unrelated to the number of circulating Dane particles.Entities:
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Year: 1980 PMID: 7392542 DOI: 10.1007/bf01477280
Source DB: PubMed Journal: Klin Wochenschr ISSN: 0023-2173