Literature DB >> 7391003

Inhibition of uterine estrogen receptor transformation by sodium molybdate.

G Shyamala, L Leonard.   

Abstract

The effects of sodium molybdate on the transformation of mouse uterine cytoplasmic estradiol . receptor complex has been studied. If molybdate is added to cytosol containing the nontransformed estradiol . receptor complex, it blocks the receptor transformation which otherwise occurs during incubation at 28 degrees C. The inhibition by molybdate is apparent both in sucrose gradient centrifugation analyses of estradiol . receptor complexes and [3H]estradiol dissociation kinetic studies. A molybdate-sensitive change of the nontransformed estradiol . receptor complex can also be inferred from behavior of the estradiol . receptor complex on low ionic strength sucrose gradients.

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Year:  1980        PMID： 7391003

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  11 in total

1.  Estradiol receptor has proteolytic activity that is responsible for its own transformation.

Authors:  G A Puca; C Abbondanza; V Nigro; I Armetta; N Medici; A M Molinari
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

2.  A novel effect of molybdate on the binding of [3H]aldosterone to gel-filtered type I receptors in brain cytosol.

Authors:  S M Emadian; W G Luttge
Journal:  Neurochem Res       Date:  1988-08       Impact factor: 3.996

3.  Interaction of the radiolabelled high-affinity anti-oestrogen [3H]H1285 with the cytoplasmic oestrogen receptor.

Authors:  J L Keene; F Sweet; M F Ruh; T S Ruh
Journal:  Biochem J       Date:  1984-02-01       Impact factor: 3.857

4.  Immunorecognition of the active form of the oestrogen receptor by using a monoclonal antibody.

Authors:  N Giambiagi; J R Pasqualini
Journal:  Biochem J       Date:  1985-08-15       Impact factor: 3.857

5.  Physicochemical and genetic evidence for specific antiestrogen binding sites.

Authors:  J C Faye; S Jozan; G Redeuilh; E E Baulieu; F Bayard
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

6.  The binding of rat uterine cytosol oestrogen receptors to oligodeoxythymidylate--cellulose. Its relationship to a stable form of receptor complex with separate ligand- and oligonucleotide-binding sites.

Authors:  L Myatt; M G Elder; C Neethling; L Lim
Journal:  Biochem J       Date:  1982-01-15       Impact factor: 3.857

7.  Effect of molybdenum supplementation on N-nitroso-N-methylurea-induced mammary carcinogenesis and molybdenum excretion in rats.

Authors:  C D Seaborn; S P Yang
Journal:  Biol Trace Elem Res       Date:  1993 Nov-Dec       Impact factor: 3.738

8.  Structural differences between the hormone and antihormone estrogen receptor complexes bound to the hormone response element.

Authors:  M Sabbah; F Gouilleux; B Sola; G Redeuilh; E E Baulieu
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-15       Impact factor: 11.205

9.  Inactivation of rat liver glucocorticoid receptor by molybdate. Effects on both non-activated and activated receptor complexes.

Authors:  N Murakami; V K Moudgil
Journal:  Biochem J       Date:  1981-09-15       Impact factor: 3.857

10.  Molybdenum-induced changes in the epiphyseal growth plate.

Authors:  N M Parry; M Phillippo; M D Reid; B A McGaw; D J Flint; N Loveridge
Journal:  Calcif Tissue Int       Date:  1993-09       Impact factor: 4.333
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