Literature DB >> 7390508

Is the HpO phenomenon in tropical populations really genetic?

A Rougemont, M Quilici, J Delmont, J P Ardissone.   

Abstract

Long-term studies of 98 unselected adults from a rural African community in Mali where malaria is endemic showed that the haptoglobin level of the blood increased significantly after 1 year of continuous anti-malarial treatment. This seems to indicate that hypo- or anhaptoglobinaemia in populations like this may in a considerable number of cases have a non-genetic basis.

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Year:  1980        PMID： 7390508     DOI： 10.1159/000153127

Source DB:  PubMed          Journal:  Hum Hered        ISSN： 0001-5652            Impact factor:   0.444


  5 in total

1.  A population genetic survey of the haptoglobin polymorphism in Melanesians by DNA analysis.

Authors:  A V Hill; D K Bowden; J Flint; D B Whitehouse; D A Hopkinson; S J Oppenheimer; S W Serjeantson; J B Clegg
Journal:  Am J Hum Genet       Date:  1986-03       Impact factor: 11.025

2.  The haptoglobin-gene deletion responsible for anhaptoglobinemia.

Authors:  Y Koda; M Soejima; N Yoshioka; H Kimura
Journal:  Am J Hum Genet       Date:  1998-02       Impact factor: 11.025

3.  A novel I247T missense mutation in the haptoglobin 2 beta-chain decreases the expression of the protein and is associated with ahaptoglobinemia.

Authors:  Kwesi Teye; Isaac K E Quaye; Yoshiro Koda; Mikiko Soejima; Hao Pang; Makoto Tsuneoka; Albert G B Amoah; Andrew Adjei; Hiroshi Kimura
Journal:  Hum Genet       Date:  2004-03-04       Impact factor: 4.132

Review 4.  A review of haptoglobin typing methods for disease association study and preventing anaphylactic transfusion reaction.

Authors:  Dae-Hyun Ko; Ho Eun Chang; Taek Soo Kim; Eun Young Song; Kyoung Un Park; Junghan Song; Kyou Sup Han
Journal:  Biomed Res Int       Date:  2013-02-28       Impact factor: 3.411

Review 5.  Current understanding of allergic transfusion reactions: incidence, pathogenesis, laboratory tests, prevention and treatment.

Authors:  Fumiya Hirayama
Journal:  Br J Haematol       Date:  2012-12-06       Impact factor: 6.998
  5 in total

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