Literature DB >> 7389797

Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistance.

A H Calvert, T R Jones, P J Dady, B Grzelakowska-Sztabert, R M Paine, G A Taylor, K R Harrap.   

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Year:  1980        PMID: 7389797     DOI: 10.1016/0014-2964(80)90214-5

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0014-2964            Impact factor:   9.162


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  6 in total

1.  Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug.

Authors:  Y Takemura; W Gibson; R Kimbell; H Kobayashi; H Miyachi; A L Jackman
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.553

2.  The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ in human leukaemia and colorectal carcinoma cell lines.

Authors:  E J Estlin; K Balmanno; A H Calvert; A G Hall; J Lunec; D R Newell; A D Pearson; G A Taylor
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

3.  Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331.

Authors:  S D Webley; A Hardcastle; R D Ladner; A L Jackman; G W Aherne
Journal:  Br J Cancer       Date:  2000-09       Impact factor: 7.640

4.  Biological activity and intracellular metabolism of ZD1694 in human leukemia cell lines with different resistance mechanisms to antifolate drugs.

Authors:  Y Takemura; H Kobayashi; H Miyachi; W Gibson; R Kimbell; A L Jackman
Journal:  Jpn J Cancer Res       Date:  1996-07

Review 5.  Clinical studies with MTA.

Authors:  A H Calvert; J M Walling
Journal:  Br J Cancer       Date:  1998       Impact factor: 7.640

6.  Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues.

Authors:  H Miyachi; Y Takemura; H Kobayashi; K Ando; Y Ando
Journal:  Jpn J Cancer Res       Date:  1993-01
  6 in total

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