Literature DB >> 7389199

BCG-induced changes in size of thymic cortex and thymus-dependent areas in spleen and lymph nodes of mice.

E M Meyer, E Grundmann.   

Abstract

Significant changes in the size of thymic cortex and of thymus-dependent areas (TDA) in spleen and lymph nodes, were revealed by histomorphometry after intraperitoneal injection of BCG into young-adult BALB/c mice. Reactions of the thymic cortex were found to be biphasic with initial involution and subsequent hyperplasia. TDA in the spleen showed a transient involution with almost complete regeneration at the end of the experiment. The response of TDA in lymph nodes was characterized by pronounced and persistent hyperplasia. The functional significance of these BCG-induced changes of lymphoid tissue compartments is discussed.

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Year:  1980        PMID： 7389199      PMCID： PMC1537931     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  17 in total

1.  A mathematical model in immunoregulation where the spleen has a pivotal role.

Authors:  J W Streilein; C B Read
Journal:  J Theor Biol       Date:  1976-09-21       Impact factor: 2.691

2.  Distinctive medullary and germinal center proliferative patterns in mouse lymph nodes after regional primary and secondary stimulation with tetanus toxoid.

Authors:  H Buerki; H Cottier; M W Hess; J Laissue; R D Stoner
Journal:  J Immunol       Date:  1974-06       Impact factor: 5.422

3.  The effect of localized injection of adjuvant material on the draining lymph node. II. Circulating lymphocytes.

Authors:  D W Dresser; R N Taub; A R Krantz
Journal:  Immunology       Date:  1970-05       Impact factor: 7.397

4.  Network of immune-neuroendocrine interactions.

Authors:  H Besedovsky; E Sorkin
Journal:  Clin Exp Immunol       Date:  1977-01       Impact factor: 4.330

Review 5.  Present knowledge of immunization against tuberculosis.

Authors:  H G Dam; K Toman; K L Hitze; J Guld
Journal:  Bull World Health Organ       Date:  1976       Impact factor: 9.408

6.  The effects of certain immunity systemic advuvants, PHA, and human gamma globulin on the thymic cortex of mice: a light and electron microscope study.

Authors:  A Khalil; H Rappaport; D Dantchev; I Florentin; C Bourut
Journal:  Biomedicine       Date:  1976-12-15

Review 7.  Lymphocyte migration and immune responses.

Authors:  W L Ford
Journal:  Prog Allergy       Date:  1975

8.  Effects of BCG on lymphocyte trapping.

Authors:  M M Zatz
Journal:  J Immunol       Date:  1976-06       Impact factor: 5.422

9.  Splenic regulation of lymphocyte trapping in lymph nodes draining tumor grafts.

Authors:  R S Fightlin; B Lytton; R K Gershon
Journal:  J Immunol       Date:  1975-08       Impact factor: 5.422

Review 10.  Studies on the immunogical effects of BCG and its components: theoritical and therapeutic implications.

Authors:  M S Mitchell
Journal:  Biomedicine       Date:  1976
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  3 in total

1.  The immunologic and immunotherapeutic sequelae of intraperitoneal BCG. II: Serial changes in spleen weight, morphology, cell populations and in vitro mitogen responses.

Authors:  W R Roche; H McLaughlin
Journal:  Ir J Med Sci       Date:  1983-08       Impact factor: 1.568

2.  Flow microfluorometry analysis of alterations in T-lymphocyte subsets during murine listeriosis.

Authors:  S R Watson; T J Redington; T B Miller; W E Bullock
Journal:  Infect Immun       Date:  1984-08       Impact factor: 3.441

3.  Resistance and susceptibility of mice to bacterial infection: histopathology of listeriosis in resistant and susceptible strains.

Authors:  T E Mandel; C Cheers
Journal:  Infect Immun       Date:  1980-12       Impact factor: 3.441
  3 in total

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