Literature DB >> 7387854

Clearance of immune complexes formed in normal and leukaemic rats.

P S Shepherd, R A Pendry, C J Dean.   

Abstract

Immune complexes of 125I-HSA-rat anti-HSA formed in vivo under conditions of antibody excess were rapidly cleared from the circulation of both normal and leukaemic Hooded rats. In HSA-immune rats most of the 125I-HSA present in the blood was found to be cell-bound, but a proportion was present as circulating immune complexes that could be precipitated from plasma by 2.5% polyethylene glycol. There was no evidence that clearance of a soluble antigen was impaired in leukaemic animals.

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Year:  1980        PMID： 7387854      PMCID： PMC2010261          DOI： 10.1038/bjc.1980.98

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  9 in total

1.  The clearance of antigen antibody complexes from the blood by the reticuloendothelial system.

Authors:  B BENACERRAF; M SEBESTYEN; N S COOPER
Journal:  J Immunol       Date:  1959-02       Impact factor: 5.422

2.  Elimination of antigen-antibody complexes from sera of rabbits.

Authors:  W O WEIGLE
Journal:  J Immunol       Date:  1958-09       Impact factor: 5.422

3.  Blocking of lymphocyte-mediated cytotoxicity for rat hepatoma cells by tumour-specific antigen-antibody complexes.

Authors:  R W Baldwin; M R Price; R A Robins
Journal:  Nat New Biol       Date:  1972-08-09

4.  A method of trace iodination of proteins for immunologic studies.

Authors:  P J McConahey; F J Dixon
Journal:  Int Arch Allergy Appl Immunol       Date:  1966

5.  Saturation of the reticuloendothelial system with soluble immune complexes.

Authors:  A O Haakenstad; M Mannik
Journal:  J Immunol       Date:  1974-05       Impact factor: 5.422

6.  Detection of immune complexes in unheated sera by modified 125I-Clq binding test. Effect of heating on the binding of Clq by immune complexes and application of the test to systemic lupus erythematosus.

Authors:  R H Zubler; G Lange; P H Lambert; P A Miescher
Journal:  J Immunol       Date:  1976-01       Impact factor: 5.422

7.  The growth patterns of two transplantable acute leukaemias of spontaneous origin in rats.

Authors:  A B Wrathmell
Journal:  Br J Cancer       Date:  1976-02       Impact factor: 7.640

8.  Persistence of hapten-antibody complexes in the circulation of immunized animals after a single intravenous injection of hapten.

Authors:  D H Schmidt; B M Kaufman; V P Butler
Journal:  J Exp Med       Date:  1974-02-01       Impact factor: 14.307

9.  Antibodies and soluble tumour-specific antigens in blood and lymph of rats with chemically induced sarcomata.

Authors:  D M Thomson; S Eccles; P Alexander
Journal:  Br J Cancer       Date:  1973-07       Impact factor: 7.640
  9 in total

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