Literature DB >> 7387779

The effect of polyunsaturated phosphatidylcholine on plasma lipids and fecal sterol excretion.

H Greten, H Raetzer, A Stiehl, G Schettler.   

Abstract

Highly polyunsaturated phosphatidylcholine (PC) was orally administered to patients with familial hypercholesterolemia and normal controls. Plasma lipid and lipoprotein composition as well as fecal sterol excretion and bile lipid composition were analyzed. Two dietary regimens were given, containing similar amounts of calories, cholesterol and polyunsaturated fatty acids in order to evaluate the specific effect of phosphorylcholine. No change in plasma lipid or lipoprotein concentration was observed. However, fecal sterol excretion was substantially increased in all subjects when PC was added to the diet. Bile acids, phospholipid and cholesterol content in bile did not vary.

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Year:  1980        PMID： 7387779     DOI： 10.1016/0021-9150(80)90201-4

Source DB:  PubMed          Journal:  Atherosclerosis        ISSN： 0021-9150            Impact factor:   5.162


  9 in total

Review 1.  From blood to gut: direct secretion of cholesterol via transintestinal cholesterol efflux.

Authors:  Carlos L J Vrins
Journal:  World J Gastroenterol       Date:  2010-12-21       Impact factor: 5.742

2.  Increased concentration of plasma cholesterol in veal calves fed soybean lecithin.

Authors:  A C Beynen; L G Van Gils
Journal:  Experientia       Date:  1983-05-15

3.  [Decrease of serum lipoproteins and increase in apolipoproteins A-I and A-II following oral administration of multiple unsaturated phospholipids. Observations on the effect of nutrition on the results].

Authors:  W Spann; G Wolfram; N Zöllner
Journal:  Klin Wochenschr       Date:  1987-07-01

4.  Influence of dietary soybean and egg lecithins on lipid responses in cholesterol-fed guinea pigs.

Authors:  B C O'Brien; S M Corrigan
Journal:  Lipids       Date:  1988-07       Impact factor: 1.880

5.  Hepatic accumulation of intestinal cholesterol is decreased and fecal cholesterol excretion is increased in mice fed a high-fat diet supplemented with milk phospholipids.

Authors:  Alvin Kamili; Elaine Wat; Rosanna Ws Chung; Sally Tandy; Jacquelyn M Weir; Peter J Meikle; Jeffrey S Cohn
Journal:  Nutr Metab (Lond)       Date:  2010-12-31       Impact factor: 4.169

6.  Dietary phospholipids and intestinal cholesterol absorption.

Authors:  Jeffrey S Cohn; Alvin Kamili; Elaine Wat; Rosanna W S Chung; Sally Tandy
Journal:  Nutrients       Date:  2010-02-08       Impact factor: 5.717

7.  Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans.

Authors:  Margreet R Olthof; Trinette van Vliet; Petra Verhoef; Peter L Zock; Martijn B Katan
Journal:  PLoS Med       Date:  2005-05-31       Impact factor: 11.069

Review 8.  Regression of Liver Steatosis Following Phosphatidylcholine Administration: A Review of Molecular and Metabolic Pathways Involved.

Authors:  D Osipova; K Kokoreva; L Lazebnik; E Golovanova; Ch Pavlov; A Dukhanin; S Orlova; K Starostin
Journal:  Front Pharmacol       Date:  2022-03-10       Impact factor: 5.810

9.  Lysophosphatidylcholine for efficient intestinal lipid absorption and lipoprotein secretion in caco-2 cells.

Authors:  Takanari Nakano; Ikuo Inoue; Shigehiro Katayama; Makoto Seo; Seiichiro Takahashi; Shigeru Hokari; Rina Shinozaki; Kazuhisa Hatayama; Tsugikazu Komoda
Journal:  J Clin Biochem Nutr       Date:  2009-08-28       Impact factor: 3.114
  9 in total

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