Literature DB >> 7386177

Hypothyroidism induced by anti-epileptic therapy.

S Aanderud, R E Strandjord.   

Abstract

Two patients on long-term anti-epileptic treatment, one with both phenytoin and carbamazepine, the other with carbamazepine, developed clinical hypothyroidism. Laboratory assays verified the diagnosis. Both patients became euthyroid and the thyroid hormone assays were normal after withdrawal of the drugs.

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Year:  1980        PMID： 7386177     DOI： 10.1111/j.1600-0404.1980.tb01501.x

Source DB:  PubMed          Journal:  Acta Neurol Scand        ISSN： 0001-6314            Impact factor:   3.209


  6 in total

Review 1.  Alteration of thyroid hormone homeostasis by antiepileptic drugs in humans: involvement of glucuronosyltransferase induction.

Authors:  M Strolin Benedetti; R Whomsley; E Baltes; F Tonner
Journal:  Eur J Clin Pharmacol       Date:  2005-11-24       Impact factor: 2.953

2.  Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement.

Authors:  Jacqueline Jonklaas; Antonio C Bianco; Andrew J Bauer; Kenneth D Burman; Anne R Cappola; Francesco S Celi; David S Cooper; Brian W Kim; Robin P Peeters; M Sara Rosenthal; Anna M Sawka
Journal:  Thyroid       Date:  2014-12       Impact factor: 6.568

3.  Changes in thyroid function tests induced by 2 month carbamazepine treatment in L-thyroxine-substituted hypothyroid children.

Authors:  F De Luca; T Arrigo; E Pandullo; M F Siracusano; S Benvenga; F Trimarchi
Journal:  Eur J Pediatr       Date:  1986-04       Impact factor: 3.183

4.  Thyroid hormone concentrations in epileptic patients.

Authors:  J G Larkin; G J Macphee; G H Beastall; M J Brodie
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

5.  Changes in circulating thyroid hormones during short-term hepatic enzyme induction with carbamazepine.

Authors:  J M Connell; W G Rapeport; S Gordon; M J Brodie
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

6.  The effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic.

Authors:  A A Connacher; D Q Borsey; M C Browning; D L Davidson; R T Jung
Journal:  Postgrad Med J       Date:  1987-10       Impact factor: 2.401
  6 in total

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