Literature DB >> 7384555

Nicergoline, an anti-aggregating agent which inhibits release of arachidonic acid from human platelet phospholipids.

M Lagarde, M Guichardant, I Ghazi, M Dechavanne.   

Abstract

Nicergoline is an inhibitor of human platelet aggregation induced by many agents. It inhibits platelet prostaglandin production induced by thrombin or collagen but not by arachidonic acid. It abolishes the decrease of platelet phospholipid induced by thrombin. Nicergoline appears as a drug with an antiphospholipase activity of human platelets.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7384555     DOI： 10.1016/s0090-6980(80)80005-0

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  3 in total

1.  Proceedings of the British Pharmacological Society. London, 17th-19th December, 1984. Abstracts.

Authors: 
Journal:  Br J Pharmacol       Date:  1985-03       Impact factor: 8.739

2.  Potentiation by adrenaline of human platelet activation and the inhibition by the alpha-adrenergic antagonist nicergoline of platelet adhesion, secretion and aggregation.

Authors:  F Lanza; J P Cazenave; A Beretz; A Sutter-Bay; J G Kretz; R Kieny
Journal:  Agents Actions       Date:  1986-08

3.  Nicergoline in senile dementia of Alzheimer type and multi-infarct dementia: a double-blind, placebo-controlled, clinical and EEG/ERP mapping study.

Authors:  B Saletu; E Paulus; L Linzmayer; P Anderer; H V Semlitsch; J Grünberger; L Wicke; A Neuhold; I Podreka
Journal:  Psychopharmacology (Berl)       Date:  1995-02       Impact factor: 4.530
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.