Literature DB >> 738434

Effect of actinomycin D or puromycin on microsomal testosterone hydroxylase activity enhanced by testosterone in female rat liver.

N Sato, M Ota, K Obara.   

Abstract

The injection of testosterone propionate for 4 successive days into female rats resulted in an increase of the in vitro conversion of the hydroxylated testosterones from testosterone by the hepatic microsomal fraction, but no change in the content of microsomal cytochrome P-450 occurred. Actinomycin D or puromycin, which was administered for 4 days with injections of testosterone propionate, prevented the enzyme induction.

Entities:  

Mesh:

Substances:

Year:  1978        PMID: 738434     DOI: 10.1007/bf01981484

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  11 in total

1.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE.

Authors:  T OMURA; R SATO
Journal:  J Biol Chem       Date:  1964-07       Impact factor: 5.157

2.  Sex difference in rate of ring A reduction of delta 4-3-keto-steroids in vitro by rat liver.

Authors:  F E YATES; A L HERBST; J URQUHART
Journal:  Endocrinology       Date:  1958-12       Impact factor: 4.736

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  The effects of actinomycin D and puromycin on the induction of the cytosol enzymes involved in the androgen metabolism by testosterone in female rat liver.

Authors:  M Ota; N Sato; Y Toyoshima; K Obara
Journal:  Endokrinologie       Date:  1977-02

5.  Metabolism in vitro of (4-14C) testosterone by liver homogenates of normal and carbon tetrachloride injured rats.

Authors:  N Sato; M Ota; K Obara
Journal:  Tohoku J Exp Med       Date:  1969-07       Impact factor: 1.848

6.  Effects of testosterone and estradiol in vivo on hepatic cortisol metabolism in vitro.

Authors:  R B Gillie; A Ruhmann-Wennhold; L R Johnson; D H Nelson
Journal:  Proc Soc Exp Biol Med       Date:  1973-01

7.  Sex differences in metabolism of testosterone by rat liver.

Authors:  M Ota; N Sato; K Obara
Journal:  J Biochem       Date:  1972-07       Impact factor: 3.387

8.  Effect of androgen and estrogen on the hydroxylation of steroid hormones by rat liver microsomes.

Authors:  R Kato; A Takahashi; Y Omori
Journal:  Endocrinol Jpn       Date:  1969-12

9.  [Sexually differentiated and sexually undifferentiated 3alpha- and 3beta-hydroxysteroid dehydrogenase activities and their intracellular localization in rat liver].

Authors:  H G Hoff; H Schriefers
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1973-05

10.  Delta4-3 beta-hydroxysteroid dehydrogenase activity in rat liver. Intracellular distribution and sex dependency.

Authors:  E R Lax; H Schriefers
Journal:  Eur J Biochem       Date:  1974-03-01
View more
  1 in total

1.  Estradiol treatment reduces a cytosol androgen binding protein in male rat liver.

Authors:  N Sato; M Ota; S Takahashi
Journal:  Experientia       Date:  1980-07-15
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.