Literature DB >> 738422

Effects of 6-hydroxydopamine on rat carotid body chief cells.

J Hansen, T Ord.   

Abstract

Administration of 6-hydroxydopamine (6-OHDA) in concentrations high enough to cause degeneration of perivascular adrenergic nerve terminals has no morphological effect on the catecholamine-storing cells of the rat carotid body. Uptake of 6-OHDA by carotid body chief cells may be more selective than that exhibited by small-intensely-fluorescent cells and other catecholamine-storing cells which are affected by 6-OHDA. Alternatively, the sustentacular cells which envelope the chief cells may provide an effective barrier against the uptake of 6-OHDA.

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Year:  1978        PMID： 738422     DOI： 10.1007/bf01981470

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Putative neurotransmitters in the carotid body. Mass fragmentographic studies.

Authors:  S Hellström
Journal:  Adv Biochem Psychopharmacol       Date:  1977

2.  New theory for receptor mechanism of carotid body chemoreceptors.

Authors:  M P Osborne; P J Butlar
Journal:  Nature       Date:  1975-04-24       Impact factor: 49.962

3.  Dopamine and other catecholamine-containing SIF cells.

Authors:  S H Koslow
Journal:  Adv Biochem Psychopharmacol       Date:  1977

4.  Loss of histochemically demonstrable catecholamines in the glomus cells of the carotid body after alpha-methyl-para-tyrosine treatment.

Authors:  M Grönblad; O Korkala
Journal:  Histochemistry       Date:  1977-04-20

5.  Effects of glucocorticoid treatment on catecholamine content and ultrastructure of adult rat carotid body.

Authors:  S Hellström; S H Koslow
Journal:  Brain Res       Date:  1976-02-06       Impact factor: 3.252

6.  An autoradiographic study of the mouse carotid body using tritiated leucine, dopa, dopamine and ATP with special reference to the chief cell as a paraneuron.

Authors:  S Kobayashi
Journal:  Arch Histol Jpn       Date:  1976-11

7.  Extraneuronal effects of 6-hydroxydopamine and extraneuronal uptake of noradrenaline. In-vivo and in-vitro studies on adrenocortical cells of lizards and rats.

Authors:  K Unsicker; I J Allan; D F Newgreen
Journal:  Cell Tissue Res       Date:  1976-10-01       Impact factor: 5.249

8.  Electron microscopic radioautographic studies of the carotid body following injections of labeled biogenic amine precursors.

Authors:  I L Chen; R D Yates
Journal:  J Cell Biol       Date:  1969-09       Impact factor: 10.539
  8 in total

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