Literature DB >> 7381690

A simple method for determining whether absorption and elimination rate constants are equal in the one-compartment open model with first-order processes.

M Bialer.   

Abstract

A simple method is presented by which one may determine if the absorption and the elimination rate constants are equal (in the one-compartment body model) using only plasma drug data. This method suggests the pertinent equation to calculate the relevent pharmacokinetic parameters.

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Year:  1980        PMID： 7381690     DOI： 10.1007/bf01059453

Source DB:  PubMed          Journal:  J Pharmacokinet Biopharm        ISSN： 0090-466X


  9 in total

1.  Consequence of equal absorption, distribution and/or elimination rate constants.

Authors:  Y Plusquellec; F Courbon; S Nogarede
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1999 Jul-Sep       Impact factor: 2.441

2.  Multiple solutions, illegal parameter values, local minima of the sum of squares, and anomalous parameter estimates in least-squares fitting of the two-compartment pharmacokinetic model with absorption.

Authors:  R D Purves
Journal:  J Pharmacokinet Biopharm       Date:  1996-02

3.  Coupled solutions of one- and two-compartment pharmacokinetic models with first-order absorption.

Authors:  N Asmanova; G Koloskov; A I Ilin
Journal:  J Pharmacokinet Pharmacodyn       Date:  2013-04-10       Impact factor: 2.745

Review 4.  Current models in pharmacokinetics: applications in veterinary pharmacology.

Authors:  L D Kinabo; Q A McKellar
Journal:  Vet Res Commun       Date:  1989       Impact factor: 2.459

5.  Pharmacokinetic model equations for the one- and two-compartment models with first-order processes in which the absorption and exponential elimination or distribution rate constants are equal.

Authors:  H P Wijnand
Journal:  J Pharmacokinet Biopharm       Date:  1988-02

6.  The Bateman function revisited: a critical reevaluation of the quantitative expressions to characterize concentrations in the one compartment body model as a function of time with first-order invasion and first-order elimination.

Authors:  E R Garrett
Journal:  J Pharmacokinet Biopharm       Date:  1994-04

7.  Simplified methods for the evaluation of the parameters of the time course of plasma concentration in the one-compartment body model with first-order invasion and first-order drug elimination including methods for ascertaining when such rate constants are equal.

Authors:  E R Garrett
Journal:  J Pharmacokinet Biopharm       Date:  1993-12

Review 8.  Pharmacodynamic model of slow reversible binding and its applications in pharmacokinetic/pharmacodynamic modeling: review and tutorial.

Authors:  Tianjing Ren; Xu Zhu; Natalie M Jusko; Wojciech Krzyzanski; William J Jusko
Journal:  J Pharmacokinet Pharmacodyn       Date:  2022-08-30       Impact factor: 2.410

9.  The impact of lag time on the estimation of pharmacokinetic parameters. I. One-compartment open model.

Authors:  N G Nerella; L H Block; P K Noonan
Journal:  Pharm Res       Date:  1993-07       Impact factor: 4.200
  9 in total

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