Literature DB >> 7380535

Cecal toxin(s) from guinea pigs with clindamycin-associated colitis, neutralized by Clostridium sordellii antitoxin.

J E Rehg.   

Abstract

The cecal contents of guinea pigs with clindamycin-associated colitis contained a heat-labile toxin. This toxin was lethal for guinea pigs and mice, produced vascular permeability in the skin of rabbits, and was cytotoxic in tissue culture. The lethality in mice, vascular permeability in rabbit skin, and cytotoxicity in tissue culture monolayers were neutralized by Clostridium sordellii antitoxin.

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Year:  1980        PMID： 7380535      PMCID： PMC550776          DOI： 10.1128/iai.27.2.387-390.1980

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  17 in total

1.  The toxins responsible for the lesions of Clostridium sordelli gas gangrene.

Authors:  S N Arseculeratne; R G Panabokké; S Wijesundera
Journal:  J Med Microbiol       Date:  1969-02       Impact factor: 2.472

2.  Lethal gram-negative bacterial superinfection in Guinea pigs given bacitracin.

Authors:  W E Farrar; T H Kent; V B Elliott
Journal:  J Bacteriol       Date:  1966-08       Impact factor: 3.490

3.  Clindamycin-associated colitis due to a toxin-producing species of Clostridium in hamsters.

Authors:  J G Bartlett; A B Onderdonk; R L Cisneros; D L Kasper
Journal:  J Infect Dis       Date:  1977-11       Impact factor: 5.226

4.  Production of vascular permeability factor by enterotoxigenic Escherichia coli isolated from man.

Authors:  D J Evans; D G Evans; S L Gorbach
Journal:  Infect Immun       Date:  1973-11       Impact factor: 3.441

5.  Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia.

Authors:  J G Bartlett; T W Chang; M Gurwith; S L Gorbach; A B Onderdonk
Journal:  N Engl J Med       Date:  1978-03-09       Impact factor: 91.245

6.  Role of clostridial toxin in the pathogenesis of clindamycin colitis in rabbits.

Authors:  J T LaMont; E B Sonnenblick; S Rothman
Journal:  Gastroenterology       Date:  1979-02       Impact factor: 22.682

7.  Clindamycin-associated enterocolitis in guinea pigs: evidence for a bacterial toxin.

Authors:  F C Knoop
Journal:  Infect Immun       Date:  1979-01       Impact factor: 3.441

8.  Pseudomembranous colitis: Presence of clostridial toxin.

Authors:  H E Larson; A B Price
Journal:  Lancet       Date:  1977 Dec 24-31       Impact factor: 79.321

9.  Clostridium difficile and the aetiology of pseudomembranous colitis.

Authors:  H E Larson; A B Price; P Honour; S P Borriello
Journal:  Lancet       Date:  1978-05-20       Impact factor: 79.321

10.  Antibiotic-induced colitis implication of a toxin neutralised by Clostridium sordellii antitoxin.

Authors:  G D Rifkin; F R Fekety; J Silva
Journal:  Lancet       Date:  1977-11-26       Impact factor: 79.321
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  11 in total

1.  Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis.

Authors:  I C Cavalcante; M V Castro; A R F Barreto; G W Sullivan; M Vale; P R C Almeida; J Linden; J M Rieger; F Q Cunha; R L Guerrant; R A Ribeiro; G A C Brito
Journal:  Infect Immun       Date:  2006-05       Impact factor: 3.441

Review 2.  Clostridium difficile: its disease and toxins.

Authors:  D M Lyerly; H C Krivan; T D Wilkins
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

3.  Transforming Growth Factor β1/SMAD Signaling Pathway Activation Protects the Intestinal Epithelium from Clostridium difficile Toxin A-Induced Damage.

Authors:  Christianne Maria Tinoco-Veras; Ana Angélica Q A Santos; Joice Stipursky; Marcelo Meloni; Ana Paula Bérgamo Araujo; Danielle Abreu Foschetti; Diana López-Ureña; Carlos Quesada-Gómez; Renata F C Leitão; Flávia Carvalho Alcantara Gomes; Gerly Anne de Castro Brito
Journal:  Infect Immun       Date:  2017-09-20       Impact factor: 3.441

4.  Adenosine deaminase inhibition prevents Clostridium difficile toxin A-induced enteritis in mice.

Authors:  Ana Flávia Torquato de Araújo Junqueira; Adriana Abalen Martins Dias; Mariana Lima Vale; Graziela Machado Gruner Turco Spilborghs; Aline Siqueira Bossa; Bruno Bezerra Lima; Alex Fiorini Carvalho; Richard Littleton Guerrant; Ronaldo Albuquerque Ribeiro; Gerly Anne Brito
Journal:  Infect Immun       Date:  2010-11-29       Impact factor: 3.441

5.  Presence of Clostridium difficile toxin in guinea pigs with penicillin-associated colitis.

Authors:  S W Rothman
Journal:  Med Microbiol Immunol       Date:  1981       Impact factor: 3.402

6.  Fucoidin prevents Clostridium difficile toxin-A-induced ileal enteritis in mice.

Authors:  A R F Barreto; I C Cavalcante; M V Castro; A F T A Junqueira; M R Vale; R A Ribeiro; M H L P Souza; G A C Brito
Journal:  Dig Dis Sci       Date:  2007-09-01       Impact factor: 3.199

Review 7.  Clostridium difficile: clinical disease and diagnosis.

Authors:  F C Knoop; M Owens; I C Crocker
Journal:  Clin Microbiol Rev       Date:  1993-07       Impact factor: 26.132

8.  Concurrence of Clostridium difficile toxin A enzyme-linked immunosorbent assay, fecal lactoferrin assay, and clinical criteria with C. difficile cytotoxin titer in two patient cohorts.

Authors:  M A Schleupner; D C Garner; K M Sosnowski; C J Schleupner; L J Barrett; E Silva; D Hirsch; R L Guerrant
Journal:  J Clin Microbiol       Date:  1995-07       Impact factor: 5.948

9.  Occurrence of toxin-producing Clostridium difficile in antibiotic-associated diarrhea in Sweden.

Authors:  B Aronsson; R Möllby; C E Nord
Journal:  Med Microbiol Immunol       Date:  1981       Impact factor: 3.402

10.  Bacillus pumilus in the induction of clindamycin-associated enterocolitis in guinea pigs.

Authors:  P F Brophy; F C Knoop
Journal:  Infect Immun       Date:  1982-01       Impact factor: 3.441
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