Literature DB >> 7380169

A new method for experimental study on gastric mucosal damage--changes in gastric mucosa of rat in hypoxemia.

S Nakazawa, K Segawa, K Imai, M Aichi, Y Tsukamoto.   

Abstract

We have demonstrated development of mucosal damage in rats maintained in a hypoxic condition. The gastric lesions were observed only in the corpus ventriculi in almost all cases, and they were rated as Ul-1 erosions histopathologically. The method has proven to facilitate the induction of long-sustained, stable hypoxemia of any desired degree in animals and is concluded to be appropriate for an experimental model of ulceration designed for the study of defensive mechanisms.

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Year:  1980        PMID： 7380169     DOI： 10.1007/bf02774933

Source DB:  PubMed          Journal:  Gastroenterol Jpn        ISSN： 0435-1339


  4 in total

1.  STUDIES ON THE DRUGS FOR PEPTIC ULCER. A RELIABLE METHOD FOR PRODUCING STRESS ULCER IN RATS.

Authors:  K TAKAGI; Y KASUYA; K WATANABE
Journal:  Chem Pharm Bull (Tokyo)       Date:  1964-04       Impact factor: 1.645

2.  Mechanism of stress ulcer. IV. Influence of fasting on the tolerance of gastric mucosal energy metabolism to ischemia and on the incidence of stress ulceration.

Authors:  R Menguy; Y F Masters
Journal:  Gastroenterology       Date:  1974-06       Impact factor: 22.682

3.  [Continuous and non-invasive measurement of hemodynamics and aerobic energy metabolism of gastric mucosa by reflectance spectrophotometry: in relation to the mechanism of acute gastric mucosal lesion (author's transl)].

Authors:  N Sato; T Kamada; M Shichiri; S Kawano; N Hayashi; A Nakagawa; T Matsumura; Y Kishida; M Fukuda; H Abe; B Hagihara
Journal:  Nihon Shokakibyo Gakkai Zasshi       Date:  1978-01

4.  Gastric ulceration following experimentally induced hypoxia and hemorrhagic shock: in vivo study of pathogenesis in rabbits.

Authors:  P T Harjola; A Sivula
Journal:  Ann Surg       Date:  1966-01       Impact factor: 12.969
  4 in total

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