Literature DB >> 7380117

A study of institutionalized mentally retarded patients in Manitoba. I: Classification and preventability.

A G Hunter, J A Evans, D R Thompson, S Ramsay.   

Abstract

This preliminary report concerns the types, and the possibility of prevention, of mental retardation found among 406 patients less than 20 years of age and with IQs less than or equal to 50 who had been admitted to institutions for the retarded in Manitoba prior to 1977. The retardation appeared to be of genetic origin in 27.8 per cent of cases, and acquired in a further 30.3 per cent. 31 per cent of the genetic and 55 per cent of the acquired, or 25.4 per cent of the total group, are considered to have been avoidable, given the full application of current techniques and knowledge.

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Year:  1980        PMID: 7380117     DOI: 10.1111/j.1469-8749.1980.tb04324.x

Source DB:  PubMed          Journal:  Dev Med Child Neurol        ISSN: 0012-1622            Impact factor:   5.449


  2 in total

1.  X-linked mental retardation with seizures and carrier manifestations is caused by a mutation in the creatine-transporter gene (SLC6A8) located in Xq28.

Authors:  Kimberly A Hahn; Gajja S Salomons; Darci Tackels-Horne; Tim C Wood; Harold A Taylor; Richard J Schroer; Herbert A Lubs; Cornelis Jakobs; Rick L Olson; Kenton R Holden; Roger E Stevenson; Charles E Schwartz
Journal:  Am J Hum Genet       Date:  2002-03-15       Impact factor: 11.025

2.  Absence of the fragile X in a group of patients with idiopathic mental retardation.

Authors:  A G Hunter; J MacDonald; J A Evans
Journal:  J Med Genet       Date:  1983-08       Impact factor: 6.318

  2 in total

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