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Literature DB >> 7379936

Intestinal degradation and absorption of the glycosidic sweeteners stevioside and rebaudioside A.

R E Wingard, J P Brown, F E Enderlin, J A Dale, R L Hale, C T Seitz.

Abstract

Contrary to prior indications, the glycosidic sweeteners stevioside and rebaudioside A are degraded to the diterpenoid aglycone steviol by rat intestinal microflora in vitro. Additional studies with steviol-17-[14C] show almost total absorption from the rat lower bowel following intracecal administration.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1980 PMID： 7379936 DOI： 10.1007/bf01965774

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

7 in total

1. Synthesis and metabolic fate of hesperetin-3-14C.

Authors: T Honohan; R L Hale; J P Brown; R E Wingard
Journal: J Agric Food Chem Date: 1976 Sep-Oct Impact factor: 5.279

2. The bile duct ligated animal: a model for determining total intestinal absorption.

Authors: S C Halladay; F E Enderlin; T M Parkinson; T Honohan
Journal: Drug Chem Toxicol Date: 1978 Impact factor: 3.356

3. Long term bile collection in the rat.

Authors: F E Enderlin; T Honohan
Journal: Lab Anim Sci Date: 1977-08

4. Frameshift mutagenicity of certain naturally occurring phenolic compounds in the 'Salmonella/microsome' test: activation of anthraquinone and flavonol glycosides by gut bacterial enzymes [proceedings].

Authors: J P Brown; P S Dietrich; R J Brown
Journal: Biochem Soc Trans Date: 1977 Impact factor: 5.407

5. Introduction to intestinal microecology.

Authors: T D Luckey
Journal: Am J Clin Nutr Date: 1972-12 Impact factor: 7.045

6. Gut microflora interactions with two experimental polymeric food additives in the rat.

Authors: J P Brown; R J Brown; B C Hyde; C M Bakner
Journal: Food Cosmet Toxicol Date: 1978-08

7. Intestinal absorption of polymeric derivatives of the food dyes sunset yellow and tartrazine in rats.

Authors: T Honohan; F E Enderlin; B A Ryerson; T M Parkinson
Journal: Xenobiotica Date: 1977-12 Impact factor: 1.908

7 in total

1. Utilisation of steviol glycosides from Stevia rebaudiana (Bertoni) by lactobacilli and bifidobacteria in in vitro conditions.

Authors: Gabriela Kunová; Vojtěch Rada; Adrien Vidaillac; Ivana Lisova
Journal: Folia Microbiol (Praha) Date: 2013-11-19 Impact factor: 2.099

2. Biological effects of stevioside on the survival of Escherichia coli strains and plasmid DNA.

Authors: A P M Nunes; J C P De Mattos; S C Ferreira-Machado; R M Nunes; N R Asad; F J S Dantas; R J A C Bezerra; A Caldeira-de-Araujo
Journal: Mol Cell Biochem Date: 2006-06-28 Impact factor: 3.396

3. The diterpene glycoside, rebaudioside A, does not improve glycemic control or affect blood pressure after eight weeks treatment in the Goto-Kakizaki rat.

Authors: Stig E U Dyrskog; Per B Jeppesen; Jianguo Chen; Lars P Christensen; Kjeld Hermansen
Journal: Rev Diabet Stud Date: 2005-08-10

7. Effects of Stevia Rebaudiana on Glucose Homeostasis, Blood Pressure and Inflammation: A Critical Review of Past and Current Research Evidence.

Authors: Justina Ray; Shweta Kumar; Daniel Laor; Naila Shereen; Felix Nwamaghinna; Alastair Thomson; Jessica Perez Perez; Lina Soni; Samy I McFarlane
Journal: Int J Clin Res Trials Date: 2021-01-22

7 in total

Intestinal degradation and absorption of the glycosidic sweeteners stevioside and rebaudioside A.

1. Synthesis and metabolic fate of hesperetin-3-14C.

2. The bile duct ligated animal: a model for determining total intestinal absorption.

3. Long term bile collection in the rat.

4. Frameshift mutagenicity of certain naturally occurring phenolic compounds in the 'Salmonella/microsome' test: activation of anthraquinone and flavonol glycosides by gut bacterial enzymes [proceedings].

5. Introduction to intestinal microecology.

6. Gut microflora interactions with two experimental polymeric food additives in the rat.

7. Intestinal absorption of polymeric derivatives of the food dyes sunset yellow and tartrazine in rats.

1. Utilisation of steviol glycosides from Stevia rebaudiana (Bertoni) by lactobacilli and bifidobacteria in in vitro conditions.

2. Biological effects of stevioside on the survival of Escherichia coli strains and plasmid DNA.

3. The diterpene glycoside, rebaudioside A, does not improve glycemic control or affect blood pressure after eight weeks treatment in the Goto-Kakizaki rat.

4. Metabolically activated steviol, the aglycone of stevioside, is mutagenic.

Review 5. The Impact of Artificial Sweeteners on Body Weight Control and Glucose Homeostasis.

6. Protective effects of Stevia rebaudiana extracts on beta cells in lipotoxic conditions.

7. Effects of Stevia Rebaudiana on Glucose Homeostasis, Blood Pressure and Inflammation: A Critical Review of Past and Current Research Evidence.