Literature DB >> 7379126

Histone mRNA metabolism during the mouse fibroblast cell cycle.

I Parker, W Fitschen.   

Abstract

The synthesis of histone mRNA in the nucleus and the eventual appearance of histone mRNA in the cytoplasm of 3T6 Swiss mouse embryo fibroblasts was investigated with a highly labelled cDNA probe complementary to histone mRNA. Very low levels of histone mRNA were found in G1 phase nuclei, with even lower levels in the cytoplasm. At the onset of DNA synthesis, there is a rapid increase in histone mRNA synthesis, with a concomitant increase of histone mRNA in the cytoplasm followed by its decline in both nucleus and cytoplasm on entering the G2 phase of the cell cycle. The decline in the nucleus is much more rapid than in the cytoplasm.

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Year:  1980        PMID： 7379126     DOI： 10.1016/0045-6039(80)90004-4

Source DB:  PubMed          Journal:  Cell Differ        ISSN： 0045-6039


  9 in total

1.  Developmental and cell cycle regulation of the Drosophila histone locus body.

Authors:  Anne E White; Michelle E Leslie; Brian R Calvi; William F Marzluff; Robert J Duronio
Journal:  Mol Biol Cell       Date:  2007-04-18       Impact factor: 4.138

Review 2.  Modifications in molecular mechanisms associated with control of cell cycle regulated human histone gene expression during differentiation.

Authors:  G S Stein; J L Stein; J B Lian; A J Van Wijnen; K L Wright; U Pauli
Journal:  Cell Biophys       Date:  1989-12

Review 3.  Regulation of specific genes during the cell cycle. Utilization of homologous cDNAs and cloned sequences for studying histone gene expression in human cells.

Authors:  G S Stein; J L Stein; F Marashi; M I Parker; L F Sierra
Journal:  Cell Biophys       Date:  1980-12

4.  Procollagen mRNA metabolism during the fibroblast cell cycle and its synthesis in transformed cells.

Authors:  I Parker; W Fitschen
Journal:  Nucleic Acids Res       Date:  1980-06-25       Impact factor: 16.971

5.  Analysis of histone gene expression during the cell cycle in HeLa cells by using cloned human histone genes.

Authors:  R Rickles; F Marashi; F Sierra; S Clark; J Wells; J Stein; G Stein
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205

6.  Is human histone gene expression autogenously regulated?

Authors:  G S Stein; J L Stein
Journal:  Mol Cell Biochem       Date:  1984-09       Impact factor: 3.396

7.  Loss of type I procollagen gene expression in SV40-transformed human fibroblasts is accompanied by hypermethylation of these genes.

Authors:  M I Parker; K Judge; W Gevers
Journal:  Nucleic Acids Res       Date:  1982-10-11       Impact factor: 16.971

8.  Intracellular distribution of histone mRNAs in human fibroblasts studied by in situ hybridization.

Authors:  J B Lawrence; R H Singer; C A Villnave; J L Stein; G S Stein
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

9.  Cell cycle-dependent expression of a stable episomal human histone gene in a mouse cell.

Authors:  L Green; I Schlaffer; K Wright; M L Moreno; D Berand; G Hager; J Stein; G Stein
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205
  9 in total

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