| Literature DB >> 7379041 |
Abstract
Eight-week-old mice of 3 sublines of strain C57BL/6 were given s.c. injections of 1,2-dimethylhydrazine (DMH), once weekly for 10 weeks. The highest incidence (85%) of colorectal tumors occurred in C57BL/6N mice. Colorectal tumors occurred in 43% of C57BL/6J mice, while only 3 (10%) C57BL/6Ha mice developed these tumors. Possible factors responsible for the differential susceptibility of 3 sublines of C57BL/6 mice to the induction of colorectal tumors by DMH are discussed.Entities:
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Year: 1980 PMID: 7379041 DOI: 10.1016/0304-3835(80)90114-7
Source DB: PubMed Journal: Cancer Lett ISSN: 0304-3835 Impact factor: 8.679