Literature DB >> 7378903

Antipyrine metabolism in man: simultaneous determination of norantipyrine and 4-hydroxyantipyrine in urine by gas chromatography.

T Inaba, N E Fischer.   

Abstract

A gas chromatographic method was developed to determine metabolites of antipyrine, norantipyhis method requires no derivatization and has ample sensitivity to determine these metabolites in urine after ingestion of antipyrine, a compound widely used as a hepatic probe of drug oxidation.

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Year:  1980        PMID： 7378903     DOI： 10.1139/y80-004

Source DB:  PubMed          Journal:  Can J Physiol Pharmacol        ISSN： 0008-4212            Impact factor:   2.273


  2 in total

1.  Genetic variation in rates of antipyrine metabolite formation: a study in uninduced twins.

Authors:  M B Penno; B H Dvorchik; E S Vesell
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

2.  Preparative isolation and purification of urinary conjugates in antipyrine metabolism in man and rat.

Authors:  J Böttcher; H Bässmann; R Schüppel; W D Lehmann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-12       Impact factor: 3.000
  2 in total

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