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Literature DB >> 7378633

Differential effects of the calcium-antagonistic vasodilators, nifedipine and verapamil, on the tracheal musculature and vasculature of the dog.

Abstract

In anaesthetized dogs the trachea in situ was perfused arterially with blood, and drugs were injected intraarterially. Isoprenaline and the calcium-antagonistic vasodilators, nifedipine and verapamil, increased tracheal blood flow and decreased resting tone of the trachea. Isoprenaline was equi-effective in producing tracheal vasodilatation and tracheal dilatation. The two calcium-antagonistic vasodilators were less effective tracheal dilators than tracheal vasodilators.

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Year: 1980 PMID： 7378633 PMCID： PMC2044226 DOI： 10.1111/j.1476-5381.1980.tb10848.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

8 in total

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8 in total

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