Literature DB >> 7378478

Ionophore-mediated cation translocation in artificial systems. II. - X537A-mediated calcium and sodium translocation.

E Couturier, W J Malaisse.   

Abstract

The ionophore X537A translocates both calcium and sodium from an aqueous into an organic solution. At non saturating cationic concentrations, each atom of calcium seems to react with two molecules of ionophore, whereas each atom of sodium apparently reacts with only one molecule of X537A. The phenomena of sodium and calcium translocation, respectively, are competitive and are both inhibited when the pH of the aqueous phase is decreased.

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Year:  1980        PMID: 7378478     DOI: 10.1016/s0300-9084(80)80193-3

Source DB:  PubMed          Journal:  Biochimie        ISSN: 0300-9084            Impact factor:   4.079


  3 in total

1.  Formation of hybrid complexes between Ca and the ionophores bromolasalocid (Br-X537A) and A23187.

Authors:  M Deleers; M Gelbcke; W J Malaisse
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

2.  Insulinotropic effects of hypoglycaemic and hyperglycaemic sulphonamides: the ionophoretic hypothesis.

Authors:  E Couturier; W J Malaisse
Journal:  Diabetologia       Date:  1980-10       Impact factor: 10.122

3.  Synergistic effects of hypoglycaemic sulphonylureas and antibiotic ionophores upon calcium translocation.

Authors:  E Couturier; W J Malaisse
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739

  3 in total

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