Literature DB >> 7378238

Response of mhs swine to i.v. infusion of lignocaine and bupivacaine.

G G Harrison, D F Morrell.   

Abstract

We report the negative response of MHS swine to i.v. infusion of lignocaine and bupivacaine yielding plasma concentrations which equal or exceed those reported in humans during extradural analgesia. It is concluded that local anaesthetic techniques using the amide-linked local anaesthetics administered in conventional dosage are safe to use in patients known to be genetically susceptible to malignant hyperthermia.

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Year:  1980        PMID: 7378238     DOI: 10.1093/bja/52.4.385

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  4 in total

1.  Amide local anaesthetics and malignant hyperthermia.

Authors:  R T Paasuke; A K Brownell
Journal:  Can Anaesth Soc J       Date:  1986-03

2.  Use of local anesthetics in malignant hyperthermia.

Authors:  A K Brownell; R T Paasuke
Journal:  CMAJ       Date:  1986-05-01       Impact factor: 8.262

3.  Effects of anesthetic and related agents on calcium-induced calcium release from sarcoplasmic reticulum isolated from rabbit skeletal muscle.

Authors:  M Wakamatsu; M Yamamoto; Y Kirino; H Katoh; H Shimonaka; Y Nozawa
Journal:  J Anesth       Date:  1989-03-01       Impact factor: 2.078

4.  Myotoxicity of local anesthetics is equivalent in individuals with and without predisposition to malignant hyperthermia.

Authors:  Sachiko Otsuki; Toshimichi Yasuda; Keiko Mukaida; Yuko Noda; Rieko Kanzaki; Hirotsugu Miyoshi; Takashi Kondo; Hiroshi Hamada; Masashi Kawamoto
Journal:  J Anesth       Date:  2018-06-25       Impact factor: 2.078

  4 in total

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